Encyclopedia of Clinical Neuropsychology

Living Edition
| Editors: Jeffrey Kreutzer, John DeLuca, Bruce Caplan


  • Anna DePold HohlerEmail author
  • Marcus Ponce de Leon
Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-56782-2_438-2



Akathisia is a syndrome characterized by unpleasant sensations of inner restlessness that manifests itself with an inability to sit still or remain motionless.

Current Knowledge

It is most often seen as a side effect of medications, mainly neuroleptic antipsychotics. Patients may have difficulty describing their symptoms, leading to a misdiagnosis of anxiety and worsening of the condition upon treatment with neuroleptic antipsychotic agents. Several medications have been used to treat the condition, including benztropine and beta-blocking agents. Withdrawal of the offending agent is often most effective. It may be seen with Parkinson’s disease.


References and Readings

  1. Kumar, A., & Calne, D. (2004). Approach to the patient with a movement disorder and overview of movement disorders. In R. L. Watts & W. C. Koller (Eds.), Movement disorders (2nd ed., p. 9). New York: McGraw-Hill.Google Scholar

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Boston University Medical CenterBostonUSA
  2. 2.William Beaumont Army Medical CenterEl PasoUSA