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Biomarker Blood Tests for Cerebral Palsy

  • Robert E. AkinsEmail author
  • Karyn G. Robinson
Living reference work entry

Abstract

Together, the multiple types of cerebral palsy (CP) represent the most common physical disability in childhood with the spastic type accounting for ~77% of cases. CP arises with a disturbance in the brain, which in most cases occurs between 24 weeks gestation and birth. Early intervention is desirable, but early diagnosis is very challenging, and diagnosis is often delayed for several months or even years. No current molecular biomarker platform readily identifies individuals with CP, but screening assays that could measure blood biomarkers, preferably collected at the time of birth, may allow for earlier diagnosis, intervention, and the development of novel therapeutics. Biomarkers that identify CP patients are needed, and multiple efforts to identify useful biomarkers in blood samples are underway. It is important to understand the nature of diagnostic biomarkers and the types of blood biomarkers being investigated in individuals with CP.

Keywords

Cerebral palsy Biomarker Blood test 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Nemours Biomedical ResearchNemours – Alfred I. duPont Hospital for ChildrenWilmingtonUSA

Section editors and affiliations

  • Steven J. Bachrach
    • 1
    • 2
  • Freeman Miller
    • 3
  1. 1.Department of Pediatrics (Emeritus)Nemours/Alfred I. duPont Hospital for ChildrenWilmingtonUSA
  2. 2.Sidney Kimmel Medical College of Thomas Jefferson UniversityPhiladelphiaUSA
  3. 3.AI DuPont Hospital for ChildrenWilmingtonUSA

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