Sensing, Signaling, and Uptake: An Introduction
The three most frequent sensing and signal transduction mechanisms in bacteria are one- and two-component systems as well as chemosensory pathways, and members of these families were found to be involved in the sensing of hydrocarbons. These systems were shown to modulate the expression of hydrocarbon degradation pathways and efflux pumps as well as to mediate hydrocarbon chemotaxis. Hydrocarbons are thought to cross the outer membrane via specific pores and the inner membrane by diffusion. However, it still remains controversial as to whether there are also active hydrocarbon uptake mechanisms.
We acknowledge financial support from FEDER funds and Fondo Social Europeo through grants from the Junta de Andalucía (grant CVI-7335) and the Spanish Ministry for Economy and Competitiveness (grants BIO2013-42297 and BIO2016-76779-P).
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