Encyclopedia of Animal Cognition and Behavior

Living Edition
| Editors: Jennifer Vonk, Todd Shackelford

Single Nucleotide Polymorphism (SNP)

  • Runjhun Mathur
  • Bhisham Singh Rana
  • Abhimanyu Kumar Jha
Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-47829-6_2049-1

Synonyms

Definition

SNPs are single nucleotide changes in genomic DNA at which different nucleotides occur in different individuals of a population. Each nucleotide at such a position denotes an allele of the SNP.

Introduction

Single nucleotide polymorphisms (SNPs), pronounced as “Snips,” is the common type of variation found in DNA between genes (Genetics Home Reference). Each SNP differs by a single DNA block represented as nucleotide. For example, a SNP may be replaced by adenine (A) in place of guanine (G) in a stretch of DNA. SNPs, if falling under coding region of genes, do not alter the amino acid sequence and, in turn, the sequence of protein produced. They are classified into two parts: synonymous, i.e., genes that do not bring any change in protein, and nonsynonymous, i.e., genes that bring change in amino acid sequence, which may be a missense (resulting in incorrect amino acid) or nonsense (not coding for any amino acid).

SNP density of existence can be...

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Runjhun Mathur
    • 1
  • Bhisham Singh Rana
    • 1
  • Abhimanyu Kumar Jha
    • 1
    • 2
  1. 1.Department of BiotechnologyIMS Engineering CollegeGhaziabadIndia
  2. 2.Department of BiotechnologyInstitute of Applied Medicine & ResearchGhaziabadIndia

Section editors and affiliations

  • Jennifer Vonk
    • 1
  1. 1.Oakland UniversityRochesterUSA