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Differentiated Thyroid Carcinoma of Follicular Origin

  • Furio Pacini
  • Maria Grazia Castagna
  • Martin Schlumberger
Reference work entry
Part of the Endocrinology book series (ENDOCR)

Abstract

Differentiated thyroid carcinoma (DTC) includes the papillary and follicular histotypes and their variants accounting for more than 90% of all thyroid cancers. The incidence of thyroid cancer has been increasing in many countries over the last 30 years, and it is the human solid cancer at the highest increase worldwide.

Both papillary and follicular differentiated thyroid cancer have usually a good prognosis with an overall mortality of less than 10%. This excellent prognosis results from the combination of the biological properties of most thyroid carcinomas and effective primary therapy. When compared with other malignancies, thyroid cancer is probably the most curable cancer, with very high long-term survival rates, at least in the well-differentiated histotypes. However, some patients are at high risk for recurrent disease or even death. Most of these patients can be identified at the time of diagnosis with the use of well-defined prognostic indicators.

Keywords

Radioiodine Thyroid ablation Thyroid cancer Thyroglobulin rhTSH 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Furio Pacini
    • 1
  • Maria Grazia Castagna
    • 1
  • Martin Schlumberger
    • 2
  1. 1.Department of Medical, Surgical and Neurological SciencesUniversity of SienaSienaItaly
  2. 2.Department of Nuclear Medicine and Endocrine OncologyGustave Roussy and Université Paris SaclayVillejuifFrance

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