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Classification and Etiopathogenesis of Hypothyroidism

  • Luca Chiovato
  • Stefano Mariotti
  • Flavia Magri
Reference work entry
Part of the Endocrinology book series (ENDOCR)

Abstract

Hypothyroidism is a graded phenomenon characterized by a deficient thyroidal production of thyroid hormone. This condition comprises multiple functional or structural disorders, both congenital and acquired. The clinical expression of hypothyroidism varies between individuals, depending on the cause, duration, and severity of the hypothyroid state, but almost all organs and systems may be affected by a deficiency of thyroid hormone production. This chapter describes the epidemiology, multiple etiologies, and clinical manifestations of hypothyroidism.

Keywords

Hypothyroidism Subclinical hypothyroidism Classification Epidemiology Etiopathogenesis Clinical features 

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Authors and Affiliations

  1. 1.Department of Internal Medicine and Medical Therapy, University of Pavia - Unit of Internal Medicine and EndocrinologyIRCCS ICS MaugeriPaviaItaly
  2. 2.Departmet of Medical Sciences and Public HealthUniversity of CagliariMonserratoItaly

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