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Chronic Myelogenous Leukemia and Myeloproliferative Disorders in Older Adults

  • Raul CordobaEmail author
  • Valentin Garcia-Gutierrez
  • Juan M. Alonso-Dominguez
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Abstract

Chronic myeloid leukemia (CML) and other myeloproliferative neoplasms are more often diagnosed in people aged above 65. CML is more common in older adults, frequently diagnosed among people aged 65–74. Given the large proportion of older adults with these diseases, it is of interest to pay higher attention in special physiologic and comorbidity conditions found in older people. Plenty of data can be obtained from clinical trials in these diseases about tolerance, side effects, and outcome in elderly people when compared with younger people. Comorbid conditions are now being assessed in these chronic myeloproliferative diseases, with a strong correlation with toxicity and survival. Quality of life may also be improved with the new target therapy strategies approved not only in CML but also in primary myelofibrosis patients.

Keywords

Chronic myeloid leukemia Myeloproliferative neoplasms Polycythemia Essential thrombocytosis Myelofibrosis 

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Raul Cordoba
    • 1
    Email author
  • Valentin Garcia-Gutierrez
    • 2
  • Juan M. Alonso-Dominguez
    • 1
  1. 1.Department of HematologyFundación Jiménez Díaz University Hospital, Health Research Institute IIS-FJD, Autonomous University of MadridMadridSpain
  2. 2.Department of HematologyUniversity Hospital Ramón y CajalMadridSpain

Section editors and affiliations

  • Heidi Klepin
    • 1
  1. 1.Comprehensive Cancer Center of Wake Forest UniversityWinston-SalemUSA

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