Synonyms
Uremic gastritis
Definition
Uremic gastropathy is a term commonly used to describe the upper gastrointestinal signs and histopathologic changes associated with uremia, secondary to renal failure.
The clinical spectrum of upper gastrointestinal disorders in the uremic patients varies widely, since it might be influenced by several factors, such as the severity of renal function impairment, the stress level of the patients, and the assigned treatment. Gastrointestinal (GI) bleeding and dyspeptic symptoms, such as anorexia, vomiting, heartburn, and postprandial fullness, are common in these patients, although they may have no symptoms (Nardone et al. 2005). Uremic fetor (ammonia or urine-like odor to the breath) also may be present. Endoscopic and histological lesions are more frequent in symptomatic patients but may also be present in asymptomatic subjects (Khazaei et al. 2008). Hemorrhagic gastropathy is the most prevalent lesion, particularly in patients receiving chronic...
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References and Further Reading
Day, D. W., Jass, J. R., Price, A. B., Shepherd, N. A., Sloan, J. M., Talbot, I. C., Warren, B. F., Williams, G. T., et al. (2003). Morson and Dawson’s gastrointestinal pathology (4th ed.). Malden: Blackwell Science.
Khazaei, M. R., Imanieh, M. H., & Hosseini Al-Hashemi, G. (2008). Gastrointestinal evaluation in pediatric kidney transplantation candidates. Iranian Journal of Kidney Diseases, 2, 40–45.
Nardone, G., Rocco, A., Fiorillo, M., Del Pezzo, M., Autiero, G., Cuomo, R., Sarnelli, G., Lambiase, A., Budillon, G., & Cianciaruso, B. (2005). Gastroduodenal lesions and Helicobacter pylori infection in dyspeptic patients with and without chronic renal failure. Helicobacter, 10, 53–58.
Sotoudehmanesh, R., Ali Asgari, A., Ansari, R., & Nouraie, M. (2003). Endoscopic findings in end-stage renal disease. Endoscopy, 35, 502–505.
Walker, W. A., Durie, P. R., Kleinman, R., & Walker-Smith, J. A. (2004). Pediatric gastrointestinal disease, pathophysiology, diagnosis and management (4th ed.). Philadelphia: BC Decker.
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Rios, E., de Beça, F.F. (2017). Uremic Gastropathy. In: Carneiro, F., Chaves, P., Ensari, A. (eds) Pathology of the Gastrointestinal Tract. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-40560-5_1632
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DOI: https://doi.org/10.1007/978-3-319-40560-5_1632
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