Uremic gastropathy is a term commonly used to describe the upper gastrointestinal signs and histopathologic changes associated with uremia, secondary to renal failure.
The clinical spectrum of upper gastrointestinal disorders in the uremic patients varies widely, since it might be influenced by several factors, such as the severity of renal function impairment, the stress level of the patients, and the assigned treatment. Gastrointestinal (GI) bleeding and dyspeptic symptoms, such as anorexia, vomiting, heartburn, and postprandial fullness, are common in these patients, although they may have no symptoms (Nardone et al. 2005). Uremic fetor (ammonia or urine-like odor to the breath) also may be present. Endoscopic and histological lesions are more frequent in symptomatic patients but may also be present in asymptomatic subjects (Khazaei et al. 2008). Hemorrhagic gastropathy is the most prevalent lesion, particularly in patients receiving chronic...
References and Further Reading
- Nardone, G., Rocco, A., Fiorillo, M., Del Pezzo, M., Autiero, G., Cuomo, R., Sarnelli, G., Lambiase, A., Budillon, G., & Cianciaruso, B. (2005). Gastroduodenal lesions and Helicobacter pylori infection in dyspeptic patients with and without chronic renal failure. Helicobacter, 10, 53–58.CrossRefGoogle Scholar
- Walker, W. A., Durie, P. R., Kleinman, R., & Walker-Smith, J. A. (2004). Pediatric gastrointestinal disease, pathophysiology, diagnosis and management (4th ed.). Philadelphia: BC Decker.Google Scholar