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Pathology of the Gastrointestinal Tract pp 230–233Cite as

Eosinophilic Gastritis

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Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

“Allergic” gastroenteritis; Eosinophilic gastroenteritis

Definition

Eosinophilic gastritis is characterized by a prominent eosinophil-rich inflammation in the gastric wall (Lash et al. 2009) without known cause. Isolated gastric eosinophilia is very rare and it is usually associated with involvement of the duodenum, esophagus, or other gastrointestinal (GI) segments, which is also referred as eosinophilic gastroenteritis (Lash et al. 2009).

As the gastric mucosa has a variable number of eosinophils, the diagnosis, especially in biopsy material, can be difficult. One study addressed the number of eosinophil counts in the normal gastric mucosa and other eosinophil-rich entities in the stomach and the authors proposed working diagnostic criteria: (1) patients who have gastric biopsies that show an average density of >127 eosinophils/mm2(or ≥30 eosinophils per HPF in microscopes equipped with wide-lens oculars) and (2) patients that have no known associated causes of...

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References and Further Reading

  • Fenoglio-Preiser, C. M., Noffsinger, A. E., Stemmermann, G. N., Lantz, P. E., & Isaacson, P. G. (2008). The nonneoplastic stomach. In J. McGouh & J. Pine (Eds.), Gastrointestinal pathology an atlas and text (pp. 196–197). Philadelphia: Lippincott Williams & Wilkins.

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  • Holroyd, D. J., Banerjee, S., Chaudhary, K. S., et al. (2010). Transmural eosinophilic gastritis with gastric outlet obstruction: Case report and review of the literature. Annals of the Royal College of Surgeons of England, 92(4), W18–W20.

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  • Lash, R. H., Lawuers, G. Y., Odze, R. D., & Genta, R. M. (2009). Inflammatory disorders of the stomach. In R. Odze & J. Goldblum (Eds.), Surgical pathology of the GI tract, liver, biliary tract and pancreas. Philadelphia: Saunders.

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  • Lwin, T., Melton, S. D., & Genta, R. M. (2011). Eosinophilic gastritis: Histopathological characterization and quantification of the normal gastric eosinophil content. Modern Pathology, 24, 4,556–563.

    Article  Google Scholar 

  • Robert, M. E. (2009). Inflammatory disorders of the small intestine. In R. Odze & J. Goldblum (Eds.), Surgical pathology of the GI tract, liver, biliary tract and pancreas. Philadelphia: Saunders.

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  • Rothenberg, M. E. (2004). Eosinophilic gastrointestinal disorders (EGID). The Journal of Allergy and Clinical Immunology, 113(1), 11–28.

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Serviço de Anatomia Patológica, Centro Hospitalar de São João, Porto, Portugal

    Helena Baldaia

Authors
  1. Helena Baldaia
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Corresponding author

Correspondence to Helena Baldaia .

Editor information

Editors and Affiliations

  1. Faculty of Medicine of Porto University, Centro Hospitalar São João and Ipatimup/i3S, Porto, Portugal

    Fátima Carneiro

  2. Serviço de Anatomia Patológica, Instituto Português de Oncologia de Lisboa de Francisco Gentil, Lisbon, Portugal

    Paula Chaves

  3. Faculdade de Ciências da Saúde, Universidade da Beira Interior, Covilhã, Portugal

    Paula Chaves

  4. Department of Pathology, Ankara University Medical School, Sihhiye, Ankara, Turkey

    Arzu Ensari

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Cite this entry

Baldaia, H. (2017). Eosinophilic Gastritis. In: Carneiro, F., Chaves, P., Ensari, A. (eds) Pathology of the Gastrointestinal Tract. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-40560-5_1613

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  • DOI: https://doi.org/10.1007/978-3-319-40560-5_1613

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-40559-9

  • Online ISBN: 978-3-319-40560-5

  • eBook Packages: MedicineReference Module Medicine

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