Definition
Juvenile polyps are hamartomatous polyps of the gastrointestinal (GI) tract. As such, they are composed of indigenous elements to the site of origin, although arranged in a malformed manner.
Juvenile polyps can appear as solitary sporadic polyps of the colon or, less frequently, in the context of a generalized polyposis syndrome, juvenile polyposis (JP). The diagnostic criteria established for juvenile polyposis are:
- 1.
More than three to five juvenile polyps of the colorectum
- 2.
Juvenile polyps throughout the gastrointestinal tract
- 3.
Any number of juvenile polyps with a family history of juvenile polyposis (Offerhaus and Howe 2010)
JP can be clinically divided into three subtypes. The rare juvenile polyposis of infancyis a generalized polyposis syndrome usually diagnosed before the age of 2. These infants suffer from diarrhea, hemorrhage, malnutrition, and intussusception. Death occurs at an early age, and many of these patients have associated congenital anomalies...
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences and Further Reading
Brosens, L. A., Langeveld, D., van Hattem, W., et al. (2011). Juvenile polyposis syndrome. World Journal of Gastroenterology, 28(17), 4839–4844.
Calva, D., & Howe, J. (2008). Hamartomatous polyposis syndromes. The Surgical Clinics of North America, 88(4), 779.
Fenoglio-Preiser, C. M., Noffsinger, A. E., Stemmermann, G. N., Lantz, P. E., & Isaacson, P. G. (2008). Polyposis and hereditary cancer syndromes. In J. McGouh & J. Pine (Eds.), Gastrointestinal pathology an atlas and text (pp. 704–724). Philadelphia: Lippincott Williams & Wilkins.
Gammon, A., Jasperson, K., Kohlmann, W., & Burt, R. W. (2009). Hamartomatous polyposis syndromes. Best Practice & Research Clinical Gastroenterology, 23(2), 219–231.
Hornick, J. L., & Odze, R. D. (2009). Polyps of the large intestine. In R. Odze & J. Goldblum (Eds.), Surgical pathology of the GI tract, liver, biliary tract and pancreas. Philadelphia: Saunders.
Iacobuzio-Donahue, C. A. (2012). Gastrointestinal polyposis syndromes. In C. A. Iacobuzio-Donahue, E. Montgomary, & J. R. Golblum (Eds.), Gastrointestinal and liver pathology (pp. 399–402). Philadelphia: Saunders.
Offerhaus, G. J. A., & Howe, J. R. (2010). Juvenile polyposis. In F. T. Bosman, F. Carneiro, R. H. Hruban, & N. D. Theise (Eds.), WHO classification of tumours of the digestive system (pp. 166–167). Lyon: IARC.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer-Verlag Berlin Heidelberg
About this entry
Cite this entry
Baldaia, H. (2017). Juvenile Polyp, Upper Gastrointestinal Tract. In: Carneiro, F., Chaves, P., Ensari, A. (eds) Pathology of the Gastrointestinal Tract. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-40560-5_1603
Download citation
DOI: https://doi.org/10.1007/978-3-319-40560-5_1603
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-40559-9
Online ISBN: 978-3-319-40560-5
eBook Packages: MedicineReference Module Medicine