Basaloid Squamous Cell Carcinoma, Esophageal
There are no current synonyms for this neoplasm. Historically, it has been confused with another neoplastic entity, namely adenoid cystic carcinoma.
A malignant epithelial neoplasm composed of closely packed cells with hyperchromatic nuclei and scant cytoplasm, with a solid growth pattern, small cystic spaces, and foci of necrosis. The diagnosis depends on the demonstration of squamous cell dysplasia/carcinoma in situ in the overlying mucosa.
Basaloid squamous cell carcinoma (BSCC) is a rare entity and there are no global worldwide incidence data available. In most published series, the incidence ranges from 0.07% to 11.3% of all esophageal carcinomas.
In the published series, the mean age at the time of diagnosis is around 60 years.
There is a slight predominance in males.
This type of neoplasm has been classically described in the upper aerodigestive tract, namely at the larynx and the esophagus, but it can also be...
References and Further Reading
- Imamhasan, A., Mitomi, H., Saito, T., Hayashi, T., Takahashi, M., Kajiyama, Y., & Yao, T. (2012). Immunohistochemical and oncogenetic analyses of the esophageal basaloid squamous cell carcinoma in comparison with conventional squamous cell carcinomas. Human Pathology, 43(11), 2012–2023.CrossRefGoogle Scholar