Synonyms
Non-celiac sprue; Postinfectious sprue; Post-infective tropical malabsorption
Definition
Tropical sprue (TS) is a rare acquired enteropathy of unknown etiology, characterized by malabsorption, multiple nutritional deficiencies, and mucosal abnormalities in the small bowel mainly occurring among the individuals living in or visiting the tropical countries. Tropical sprue results from a nutritional deficiency, or a transmissible microorganism and/or a toxin. Malabsorption is usually initiated by an infection followed by colonization of the small bowel by enterotoxigenic bacteria. Several microorganisms have been suspected, but none are common to all patients. Genetic or ethnic predispositions have also been suggested. Symptoms of TS include chronic non-bloody diarrhea, weight loss, bloating, and abdominal cramps. Physical examination may reveal pallor, angular stomatitis, glossitis, mouth ulcers, and peripheral edema due to protein deficiency. Anemia related to B12and folic...
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences and Further Reading
Batheja, M. J., Leighton, J., Azueta, A., & Heigh, R. (2010). The face of tropical sprue in 2010. Case Reports in Gastroenterology, 19, 168–172.
Ghoshal, U. C., & Ranjan, P. (2011). Post-infectious irritable bowel syndrome: The past, the present and the future. Journal of Gastroenterology and Hepatology, 26(Suppl 3), 94–101.
Ghoshal, U. C., Ghoshal, U., Ayyagari, A., et al. (2003). Tropical sprue is associated with contamination of small bowel with aerobic bacteria and reversible prolongation of orocecal transit time. Journal of Gastroenterology and Hepatology, 18, 540–7.
Ramakrishna, B. S., Venkataraman, S., & Mukhopadhya, A. (2006). Tropical malabsorption. Postgraduate Medical Journal, 82, 779–787.
Veitch, A. M., Kelly, P., Zulu, I. S., et al. (2001). Tropical enteropathy: A T-cell-mediated crypt hyperplastic enteropathy. European Journal of Gastroenterology and Hepatology, 13, 1175–81.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this entry
Cite this entry
Ensari, A. (2017). Tropical Sprue. In: Carneiro, F., Chaves, P., Ensari, A. (eds) Pathology of the Gastrointestinal Tract. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-40560-5_1543
Download citation
DOI: https://doi.org/10.1007/978-3-319-40560-5_1543
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-40559-9
Online ISBN: 978-3-319-40560-5
eBook Packages: MedicineReference Module Medicine