Cerebrospinal Fluid hydrodynamics in Craniosynostosis

  • Gregory JamesEmail author
  • Dominic N. P. Thompson
Living reference work entry


Hydrocephalus presents specific challenges – in both diagnosis and management – in patients with craniosynostosis. Hydrocephalus has been recognized as a feature of the syndromic forms, in particular the more phenotypically severe, for a long time. Controversy still exists regarding the pathophysiology, prevalence, and optimal management strategy of hydrocephalus in children affected by syndromic craniosynostosis. In this chapter, we review the literature and our experience regarding each of these important facets, with an attempt made to offer some unifying theories and practical guides to management. In addition, we will review specific considerations, including the association of hydrocephalus, craniosynostosis, and Chiari 1, as well as the use of craniofacial surgery for skull deformity induced either by hydrocephalus itself or its treatment.


Hydrocephalus Craniosynostosis Chiari 1 Crouzon Apert Pfeiffer 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of NeurosurgeryGreat Ormond Street HospitalLondonUK
  2. 2.Developmental Neurosciences Programme, Great Ormond Street Institute of Child HealthUniversity College LondonLondonUK

Section editors and affiliations

  • Giuseppe Cinalli
    • 1
  1. 1.Department of Pediatric NeurosurgerySantobono-Pausilipon Children’s HospitalNaplesItaly

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