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Hypertension in Chronic Kidney Disease

  • Susan M. HalbachEmail author
Reference work entry

Abstract

Hypertension is a common feature of pediatric chronic kidney disease (CKD) and is associated with CKD progression, early markers of cardiovascular disease, and impaired neurocognitive functioning. Prospective research has demonstrated that the prevalence of hypertension in this population is higher than previously thought and that hypertension is frequently underdiagnosed and undertreated. Identifying and treating hypertension in children with CKD require familiarity with the use of pediatric normative blood pressure values and clinical guidelines as well as correct measurement technique. This includes the application of ambulatory blood pressure monitoring (ABPM), which can be helpful in both diagnosis and management. Agents which target the renin-angiotensin-aldosterone system (RAAS) are recommended as first-line therapy to treat hypertension in children with CKD, though multiple medications may be required to achieve sufficient BP control.

Keywords

Blood pressure Hypertension Chronic kidney disease Child Adolescent Cardiovascular 

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Division of Nephrology, Seattle Children’s HospitalUniversity of Washington School of MedicineSeattleUSA

Section editors and affiliations

  • Joseph T. Flynn
    • 1
    • 2
  1. 1.Division of NephrologySeattle Children’s HospitalSeattleUSA
  2. 2.Department of PediatricsUniversity of Washington School of MedicineSeattleUSA

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