Neonatal Skin Disorders
Skin is a dynamic complex organ, which accomplishes versatile functions and thus plays a key role in the maintenance of the homeostasis of the organism. At birth, the development of the skin is not fully complete. The beginning of the postnatal life is a period for active adaptation and maturation of the cutaneous structure and functions. The environment around the skin changes drastically after birth: a newborn infant goes from the warm, wet, sterile, and safe womb to a cooler, dry, bacteria-laden nursery; concurrently the baby begins the journey to self-sufficiency by breathing air, taking nutrition, and maintaining body temperature. Newborn skin is critical to this transition and performs many functions (barrier to water loss, light, and irritants; infection control and immunosurveillance; resilience to mechanical trauma; sensation and tactile discrimination; thermal regulation; and acid mantle formation).
A variety of normal and abnormal lesions may be present on newborn skin surface (including adnexa, oral mucosa, and genito-anal area). Although these findings are often benign, it is important to distinguish them and to be aware about the nature of the disease, to manage them properly.
- Sa J, Khachemoune A, Guldbakke KK (2007) Piebaldism: a case report and a concise review of the literature. Cutis 80:411–414Google Scholar