Neonatology pp 791-799 | Cite as

Meconium Aspiration Syndrome

  • Simone Pratesi
  • Carlo DaniEmail author
Reference work entry


Meconium aspiration syndrome is a disease characterized by a respiratory insufficiency of variable severity, where lung injury probably starts prenatally. The role of meconium in the pathogenesis of the disease is still partly unknown, while increasing evidence suggests that chronic in utero insults may be responsible for starting lung damage as well as triggering fetal distress and meconium passage into the amniotic fluid. Survival rate has greatly improved over the last three decades with newer and more efficient modalities of treatment. On the other hand, concern exists about the long-term neurodevelopmental and pulmonary outcome of survivors.



Extracorporeal membrane oxygenation


High-frequency oscillatory ventilation


Inhaled nitric oxide


Meconium aspiration syndrome


Meconium-stained amniotic fluid


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Neonatal Intensive Care UnitCareggi University HospitalFlorenceItaly
  2. 2.Università degli Studi di FirenzeFlorenceItaly

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