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Pleomorphic fibromas are benign polypoid stromal proliferations containing bizarre appearing and often multinucleated cells.
Rare but no accurate data exist on incidence.
There is a predilection for middle-aged adults (Kamino et al. 1989).
Females are slightly more frequently affected than males.
The extremities are most commonly affected followed by the trunk (Kamino et al. 1989).
No specific treatment is necessary and simple excision is curative.
Pleomorphic fibromas are benign.
Pleomorphic fibroma presents as solitary, flesh-colored, dome-shaped papules or polypoid nodules measuring few millimeters up to 1.5 centimeters (Kamino et al. 1989).
The tumor cells express CD34 with loss of RB1 expression. There is variable SMA expression.
The tumors closely resemble pleomorphic lipoma but lack the adipocytic component.