Myositis ossificans (MO) is a benign self-limiting, pseudosarcomatous ossifying lesion that in most cases is secondary to an obvious trauma or minor repetitive trauma.
There is a predilection for male subjects.
MO can develop at any site, but it occurs more commonly in the skeletal muscles of the lower extremities, especially the thighs and buttocks. Lesions similar to MO can develop in the subcutaneous fat (panniculitis ossificans), in the mesentery (heterotopic mesenteric ossification), in the fascia (fasciitis ossificans), or in the fingers (fibro-osseous pseudotumor of the digits).
Once the diagnosis has been reached, surgical treatment is not strictly necessary, unless the lesion causes...
References and Further Reading
- Bekers, E. M., Eijkelenboom, A., Grünberg, K., Roverts, R. C., de Rooy, J. W. J., van der Geest, I. C. M., van Gorp, J. M., Creytens, D., & Flucke, U. (2018). Myositis ossificans – Another condition with USP6 rearrangement, providing evidence of a relationship with nodular fasciitis and aneurysmal bone cyst. Annals of Diagnostic Pathology, 34, 56–59.CrossRefGoogle Scholar
- Švajdler, M., Michal, M., Martínek, P., Ptáková, N., Kinkor, Z., Szépe, P., Švajdler, P., Mezencev, R., & Michal, M. (2019). Fibro-osseous pseudotumor of digits and myositis ossificans show consistent COL1A1-USP6 rearrangement: A clinicopathological and genetic study of 27 cases. Human Pathology, 88, 39–47.CrossRefGoogle Scholar