Encyclopedia of Pathology

Living Edition
| Editors: J.H.J.M. van Krieken

Intramuscular/Intermuscular Lipoma

  • Rocco CappellessoEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-28845-1_5406-1

Synonyms

Definition

A benign tumor of mature adipocytes within (intramuscular) or between (intermuscular) skeletal muscles.

Clinical Features

  • Incidence

    Lipoma is the most common soft tissue tumor in the adulthood accounting for about one half of all soft tissue tumors (Myhre-Jensen 1981; Rydholm and Berg 1983). However, its real incidence may be underestimated. The frequency of lipoma seems to be higher in the obese population. Intramuscular/intermuscular lipoma accounts for less than 10% of all benign lipomas.

  • Age

    Intramuscular/intermuscular lipoma more frequently affects middle aged adults (usually between the fourth and sixth decades).

  • Sex

    There is a male predominance.

  • Site

    Intramuscular/intermuscular lipoma usually affects the large muscles of the thigh, shoulder, arm, and trunk.

  • Treatment

    Simple excision is the recommended treatment.

  • Outcome

    Intramuscular/intermuscular lipoma is benign with no capacity to dedifferentiate or metastasize....

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References

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  2. Kindblom, L. G., Angervall, L., Stener, B., & Wickbom, I. (1974). Intermuscular and intramuscular lipomas and hibernomas. A clinical, roentgenologic, histologic, and prognostic study of 46 cases. Cancer, 33, 754–762.CrossRefGoogle Scholar
  3. Myhre-Jensen, O. (1981). A consecutive 7-year series of 1331 benign soft tissue tumours: Clinicopathologic data. Comparison with sarcomas. Acta Orthopaedica Scandinavica, 52, 287–293.CrossRefGoogle Scholar
  4. Petit, M. M., Mols, R., Schoenmakers, E. F., Mandahl, N., & Van de Ven, W. J. (1996). LPP, the preferred fusion partner gene of HMGICin lipomas, is a novel member of the LIM protein gene family. Genomics, 36, 118–129.CrossRefGoogle Scholar
  5. Rydholm, A., & Berg, N. O. (1983). Size, site and clinical incidence of lipoma: Factors in the differential diagnosis of lipoma and sarcoma. Acta Orthopaedica Scandinavica, 54, 929–934.CrossRefGoogle Scholar
  6. Schoenmakers, E. F., Wanschura, S., Mols, R., Bullerdiek, J., Van den Berghe, H., & Van de Ven, W. J. (1995). Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours. Nature Genetics, 10, 436.CrossRefGoogle Scholar
  7. Willén, H., Åkerman, M., Dal Cin, P., De Wever, I., Fletcher, C. D., Mandahl, N., et al. (1998). Comparison of chromosomal patterns with clinical features in 165 lipomas: A report of the CHAMP study group. Cancer Genetics and Cytogenetics, 102, 46–49.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Padua University HospitalPaduaItaly