Definition
Cranial Fasciitis (CF) is a benign fibroblastic and myofibroblastic proliferative condition of the soft and hard tissues of the cranium. It is considered a variant of nodular fasciitis.
Clinical Features
Incidence
CF is rare, with approximately 70 cases reported in the literature (Lauer and Enzinger 1980; Sarangarajan and Dehner 1999; Salib et al. 2019).
Age
It usually presents in children under the age of 2 years.
Sex
CF involves more frequently males (Sarangarajan and Dehner 1999).
Site
CF typically affects the cranial vault, with a predilection for the temporal and parietal regions (Lauer and Enzinger 1980; Sarangarajan and Dehner 1999). The lesion is located in the subcutis, but bone erosion and involvement of the dura may occur (Fig. 1).
Treatment
Conservative surgical excision is the treatment of choice.
Outcome
CL is benign and recurrence is rare. Spontaneous regression may occur.
References and Further Reading
Lauer, D. H., & Enzinger, F. M. (1980). Cranial fasciitis of childhood. Cancer, 45, 401–406.
Salib, C., Edelman, M., Lilly, J., Fantasia, J. E., & Yancoskie, A. E. (2019). USP6 gene rearrangement by FISH analysis in cranial fasciitis: A report of three cases. Head and Neck Pathology. https://doi.org/10.1007/s12105-019-01018-0.
Sarangarajan, R., & Dehner, L. P. (1999). Cranial and extracranial fasciitis of childhood: A clinicopathologic and immunohistochemical study. Human Pathology, 30, 87–92.
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Franchi, A. (2020). Cranial Fasciitis. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5371-1
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DOI: https://doi.org/10.1007/978-3-319-28845-1_5371-1
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