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Cranial Fasciitis

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Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

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Definition

Cranial Fasciitis (CF) is a benign fibroblastic and myofibroblastic proliferative condition of the soft and hard tissues of the cranium. It is considered a variant of nodular fasciitis.

Clinical Features

  • Incidence

    CF is rare, with approximately 70 cases reported in the literature (Lauer and Enzinger 1980; Sarangarajan and Dehner 1999; Salib et al. 2019).

  • Age

    It usually presents in children under the age of 2 years.

  • Sex

    CF involves more frequently males (Sarangarajan and Dehner 1999).

  • Site

    CF typically affects the cranial vault, with a predilection for the temporal and parietal regions (Lauer and Enzinger 1980; Sarangarajan and Dehner 1999). The lesion is located in the subcutis, but bone erosion and involvement of the dura may occur (Fig. 1).

  • Treatment

    Conservative surgical excision is the treatment of choice.

  • Outcome

    CL is benign and recurrence is rare. Spontaneous regression may occur.

    Fig. 1
    figure 1

    Cranial fasciitis involving the occipital bone. The lesion is well-circumscribed...

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References and Further Reading

  • Lauer, D. H., & Enzinger, F. M. (1980). Cranial fasciitis of childhood. Cancer, 45, 401–406.

    Article  CAS  Google Scholar 

  • Salib, C., Edelman, M., Lilly, J., Fantasia, J. E., & Yancoskie, A. E. (2019). USP6 gene rearrangement by FISH analysis in cranial fasciitis: A report of three cases. Head and Neck Pathology. https://doi.org/10.1007/s12105-019-01018-0.

  • Sarangarajan, R., & Dehner, L. P. (1999). Cranial and extracranial fasciitis of childhood: A clinicopathologic and immunohistochemical study. Human Pathology, 30, 87–92.

    Article  CAS  Google Scholar 

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Correspondence to Alessandro Franchi .

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Franchi, A. (2020). Cranial Fasciitis. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5371-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_5371-1

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  • Print ISBN: 978-3-319-28845-1

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