Encyclopedia of Pathology

Living Edition
| Editors: J.H.J.M. van Krieken

Cranial Fasciitis

  • Alessandro FranchiEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-28845-1_5371-1

Definition

Cranial Fasciitis (CF) is a benign fibroblastic and myofibroblastic proliferative condition of the soft and hard tissues of the cranium. It is considered a variant of nodular fasciitis.

Clinical Features

  • Incidence

    CF is rare, with approximately 70 cases reported in the literature (Lauer and Enzinger 1980; Sarangarajan and Dehner 1999; Salib et al. 2019).

  • Age

    It usually presents in children under the age of 2 years.

  • Sex

    CF involves more frequently males (Sarangarajan and Dehner 1999).

  • Site

    CF typically affects the cranial vault, with a predilection for the temporal and parietal regions (Lauer and Enzinger 1980; Sarangarajan and Dehner 1999). The lesion is located in the subcutis, but bone erosion and involvement of the dura may occur (Fig. 1).

  • Treatment

    Conservative surgical excision is the treatment of choice.

  • Outcome

    CL is benign and recurrence is rare. Spontaneous regression may occur.
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References and Further Reading

  1. Lauer, D. H., & Enzinger, F. M. (1980). Cranial fasciitis of childhood. Cancer, 45, 401–406.CrossRefGoogle Scholar
  2. Salib, C., Edelman, M., Lilly, J., Fantasia, J. E., & Yancoskie, A. E. (2019). USP6 gene rearrangement by FISH analysis in cranial fasciitis: A report of three cases. Head and Neck Pathology.  https://doi.org/10.1007/s12105-019-01018-0.
  3. Sarangarajan, R., & Dehner, L. P. (1999). Cranial and extracranial fasciitis of childhood: A clinicopathologic and immunohistochemical study. Human Pathology, 30, 87–92.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Translational Research and of New Technologies in Medicine and SurgeryUniversity of PisaPisaItaly