Lesion with endocervical-type mucinous epithelium involving the wall of the urinary bladder.
Bladder posterior wall or posterior dome.
Partial cystectomy may be required.
2–5 cm mass of the bladder wall.
Immunohistochemically, the endocervicosis is positive for cytokeratin (CK) 7, estrogen receptor, CKAE1/AE3, CAM5.2, and CA19-9, and negative for CK20, CDX2, MUC5AC, and progesterone receptor.
The differential diagnosis of bladder endocervicosis includes bladder adenocarcinoma and glandular cystitis. Both pathologic features and the immunohistochemical profile can be of assitance. Rarely, primary adenocarcinoma may arise in endocervicosis (Nakaguro et al. 2016).
References and Further Reading
- Young, R. H., & Clement, P. B. (1992). Endocervicosis of the urinary bladder. A report of six cases of a benign mullerian lesion that may mimic adenocarcinoma. The American Journal of Surgical Pathology, 216, 533–542.Google Scholar