Solid Papillary Carcinoma
Solid papillary carcinoma (SPC) is described in the 2012 WHO classification within the group of the intraductal papillary lesions and is defined as a variant of papillary carcinoma characterized by multiple solid nodules of neoplastic cells arranged around multiple fibrovascular spaces. Despite the lack of the external myoepithelial layer, these lesions are currently considered as noninvasive (Lakhani et al. 2012). However, cases of true invasive SPC exist.
SPC is a rare entity, accounting for 1–2% of breast carcinomas (BCs) (Otsuki et al. 2007).
It usually affects women in the seventh decade, with a mean age of 73.2 years (Maluf and Koerner 1995).
It is more frequently observed in female patients, but it has been sporadically described in men (Nassar et al. 2006).
SPC is typically unifocal and localized in the central region of the breast (Guo et al. 2016), although a single...
References and Further Reading
- Lakhani, S. R., Ellis, I. O., Schnitt, S. J., Tan, P. H., van de Vijver, M. J. (2012). WHO classification of tumours of the breast. World Health Organization classification of tumours. Lyon, IARC press. ISBN-10: 9283224337.Google Scholar