Encyclopedia of Pathology

Living Edition
| Editors: J.H.J.M. van Krieken

Angioimmunoblastic T-Cell Lymphoma

  • Laurence de LevalEmail author
  • Bettina Bisig
Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-28845-1_3862-1



Angioimmunoblastic T-cell lymphoma (AITL) is a neoplasm of mature T follicular helper (TFH) cells characterized by systemic disease, a polymorphous infiltrate involving lymph nodes, with a prominent proliferation of high endothelial venules and follicular dendritic cells (Swerdlow et al. 2017).

Clinical Features

  • Incidence

According to a retrospective study published in 2008, AITL represents the second most common form peripheral T-cell lymphoma (PTCL) worldwide, accounting for 18.5% of the cases. The disease is more common in Europe (representing 29% of the cases) than in North America or Asia where its prevalence is estimated to be 16% and 18% of the cases, respectively. According to recent publications reporting on the findings derived from the Lymphopath network in France, AITL...
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References and Further Reading

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© Springer Nature Switzerland AG 2018

Authors and Affiliations

  1. 1.Institute of PathologyUniversity Hospital Lausanne CHUVLausanneSwitzerland