Anatomy and Physiology of the Pancreas

  • M. RosenzweigEmail author
  • E. Grodstein
Living reference work entry
Part of the Organ and Tissue Transplantation book series (OTT)


Mastery of the anatomy and physiology of the pancreas is fundamental in understanding the concepts involved in Pancreas transplantation. Normal anatomy and physiology are critical to appreciating the pathology of any organ system. The indications for transplantation require knowledge of both the normal and pathological states of the involved organ. A firm grasp of the blood supply, drainage, surrounding visceral anatomy, as well as the anatomical considerations of endocrine and exocrine pancreatic physiology are essential to graft function and survival. While this chapter’s main focus is anatomy and physiology, the transplantation of the pancreas requires a multidisciplinary approach. As such, there are a number of topics that crossover with other chapters of this text. We will highlight those specific subjects and how they pertain to the core of this section. Upon completion of this chapter, the reader should feel comfortable with pancreas anatomy and physiology and how these concepts will impact pancreatic transplantation.


Endocrine pancreas Exocrine pancreas Diabetes Islet cells Proteases 



We express our gratitude to the contributing authors who granted us access to their photographs for reproduction in this chapter:

1. Gorelick and Jamieson (2005), Fig. 3.

2. Hruban et al. (2007), Figs. 1 and 2a, b.

3. Longnecker (2014), Fig. 4.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Hackensack University Medical Center-PalisadesNorth BergenUSA
  2. 2.Northwell HealthManhassetUSA

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