2020 Edition
| Editors: Maria Rosaria Raspollini, Antonio Lopez-Beltran

Teratoma, Prepubertal-Type

  • Maurizio ColecchiaEmail author
  • Alessia Bertolotti
Reference work entry
DOI: https://doi.org/10.1007/978-3-030-41894-6_4957


Benign postpubertal testicular teratoma; Dermoid cyst; Type I germ cell tumor of the testis


A tumor usually seen in the prepubertal testis (but it encompasses all age groups) composed of tissue derived from one or more of different germinal layers.

Clinical Features

  • Incidence

    Teratomas are, after YST, the second most frequent (14–20%) GCT in infancy.

  • Age

    This tumor occurs before puberty, while when occurring in older patients they may have been present but undiagnosed since childhood. They typically occur before the age of 6 years, the oldest reported patient being 59 years with an average age of 20 months.

  • Site


  • Treatment

    Conservative treatment is appropriate.

  • Outcome

    Actually no documented cases have exhibited malignant behavior (Zhang et al. 2013). The exception is carcinoid tumor that has a metastatic potential.


Grossly prepubertal-type teratoma occurs as a solid nodule or with a cystic component filled with keratinous (Fig. 1) or mucoid...
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References and Further Reading

  1. Ulbright, T. M., & Srigley, J. R. (2001). Dermoid cyst of the testis: A study of five postpubertal cases, including a pilomatrixoma-like variant, with evidence supporting its separate classification from mature testicular teratoma. The American Journal of Surgical Pathology, 25(6), 788–793.CrossRefGoogle Scholar
  2. Wang, W. P., Guo, C., Berney, D. M., Ulbright, T. M., Hansel, D. E., Shen, R., Ali, T., & Epstein, J. I. (2010). Primary carcinoid tumors of the testis: A clinicopathologic study of 29 cases. The American Journal of Surgical Pathology, 34(4), 519–524.CrossRefGoogle Scholar
  3. Zhang, C., Berney, D. M., Hirsch, M. S., Cheng, L., & Ulbright, T. M. (2013). Evidence supporting the existence of benign teratomas of the postpubertal testis: A clinical, histopathologic, and molecular genetic analysis of 25 cases. The American Journal of Surgical Pathology, 37(6), 827–835.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Uropathology Unit, Department of PathologyFondazione IRCCS Istituto Nazionale dei Tumori di MilanoMilanItaly
  2. 2.Department of PathologyFondazione IRCCS Istituto Nazionale dei Tumori di MilanoMilanItaly