Uropathology

2020 Edition
| Editors: Maria Rosaria Raspollini, Antonio Lopez-Beltran

Spermatic Cord Cellular Angiofibroma

  • Raffaele Gaeta
  • Alessandro FranchiEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-030-41894-6_4942
  • 2 Downloads

Synonyms

Angiomyofibroblastoma-like tumor

Definition

Rare, circumscribed, slow-growing, benign mesenchymal tumor whose suggested histogenesis is perivascular stem cells.

Clinical Features

  • Incidence

    Very low. About 60 cases of cellular angiofibroma in male genitourinary system are reported in English literature.

  • Age

    It affects adults usually over 50 years of age.

  • Site

    In men, cellular angiofibroma is observed in the inguino-scrotal region (paratesticular, tunica vaginalis, epididymis, and spermatic cord). There are rare reports of perineal, urethral, and retroperitoneal locations.

  • Treatment

    Recommended treatment is the complete surgical excision with tumor-free margins and long-term follow-up exams. No indications for radiation and chemotherapy.

  • Outcome

    Follow-up is required because it may recur years after initial resection. No metastases have been observed.

Macroscopy

Macroscopic appearance is of a well-circumscribed, elastic-hard, slightly mobile mass whose size varies between 2.5 cm...

This is a preview of subscription content, log in to check access.

References and Further Reading

  1. Aydin, M., Uzuner, H., Akgunes, E., et al. (2017). Cellular angiofibroma of the spermatic cord. Aktuelle Urologie, 48(2), 159–160.PubMedCrossRefGoogle Scholar
  2. Dikaiakos, P., Zizi-Sermpetzoglou, A., Rizos, S., & Marinis, A. (2011). Angiofibroma of the spermatic cord: A case report and a review of the literature. Journal of Medical Case Reports, 30(5), 423.CrossRefGoogle Scholar
  3. Iwasa, Y., & Fletcher, C. D. (2004). Cellular angiofibroma: Clinicopathologic and immunohistochemical analysis of 51 cases. The American Journal of Surgical Pathology, 28, 1426–1435.PubMedCrossRefGoogle Scholar
  4. Laskin, W. B., Fetsch, J. F., & Mostofi, F. K. (1998). Angiomyofibroblastomalike tumor of the male genital tract: Analysis of 11 cases with comparison to female angiomyofibroblastoma and spindle cell lipoma. The American Journal of Surgical Pathology, 22, 6–16.PubMedCrossRefGoogle Scholar
  5. Nucci, M. R., Granter, S. R., & Fletcher, C. D. (1997). Cellular angiofibroma: A benign neoplasm distinct from angiomyofibroblastoma and spindle cell lipoma. The American Journal of Surgical Pathology, 21, 636–644.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Translational Research and of New Technologies in Medicine and SurgeryUniversity of PisaPisaItaly