Uropathology

2020 Edition
| Editors: Maria Rosaria Raspollini, Antonio Lopez-Beltran

Solitary Fibrous Tumor of the Kidney

  • Anna Caliò
  • Diego Segala
  • Guido MartignoniEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-030-41894-6_4940
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Definition

A rare mesenchymal tumor characterized by hemangiopericytomatous pattern

Clinical Features

  • Incidence

    Intrarenal solitary fibrous tumor is a rare neoplasm.

  • Age

    It usually arises in middle-aged adults.

  • Sex

    There is no gender predominance.

  • Site

    There is no site predilection.

  • Treatment

    The complete surgical resection is the first choice of therapy if feasible.

  • Outcome

    Intrarenal solitary fibrous tumor shows an indolent behavior. However, aggressive cases have been reported (Hsieh et al. 2011).

Macroscopy

Well-circumscribed solitary mass with white, firm cut surface

Microscopy

The histologic appearance is the same as the pleural tumor, characterized by spindle cells with bland nuclear feature without a specific pattern, thick bands of collagen, and prominent branching and hyalinized vessels (Fig. 1) (Kuroda et al. 2014; Wang et al. 2001).
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References and Further Reading

  1. Hsieh, T.-Y., Chang Chien, Y.-C., Chen, W.-H., et al. (2011). De novo malignant solitary fibrous tumor of the kidney. Diagnostic Pathology, 6, 96.PubMedPubMedCentralCrossRefGoogle Scholar
  2. Kuroda, N., Ohe, C., Sakaida, N., et al. (2014). Solitary fibrous tumor of the kidney with focus on clinical and pathobiological aspects. International Journal of Clinical and Experimental Pathology, 7, 2737–2742.PubMedPubMedCentralGoogle Scholar
  3. Saeed, O., Zhang, S., Cheng, L., et al. (2019). STAT6 expression in solitary fibrous tumor and histologic mimics: A single institution experience. Applied Immunohistochemistry & Molecular Morphology.  https://doi.org/10.1097/PAI.0000000000000745. [Epub ahead of print].
  4. Wang, J., Arber, D. A., Frankel, K., et al. (2001). Large solitary fibrous tumor of the kidney report of two cases and review of the literature. The American Journal of Surgical Pathology, 25, 1194–1199.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Diagnostic and Public Health, Section of PathologyUniversity of VeronaVeronaItaly
  2. 2.Department of PathologyPederzoli HospitalPeschiera del GardaItaly