2020 Edition
| Editors: Maria Rosaria Raspollini, Antonio Lopez-Beltran

Renal Sinus Lipomatosis

  • Alessia Cimadamore
  • Rodolfo MontironiEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-030-41894-6_4927


Renal replacement lipomatosis


A condition of benign proliferation of adipose tissue within renal sinus, hilum, and perirenal space, replacing the renal parenchyma. Renal replacement lipomatosis is characterized by complete replacement of the kidney by adipose tissue, with varying degrees of fibrosis (Ratkal et al. 2015).

Clinical Features

  • Incidence


  • Age

    Any age.

  • Sex

    Both male and female.

  • Site

    Renal sinus, hilum, and perirenal space.

  • Treatment


  • Outcome



The kidney is usually enlarged and presents with a gross fibro-fatty appearance and renal cortical atrophy. It is usually associated with chronic pyelonephritis, renal lithiasis, and hydronephrosis. The shape of the kidney is always preserved (Rha et al. 2004).


The renal cortex is extremely atrophied, with varying degrees of hydronephrosis or pyonephrosis as well as acute and chronic pyelonephritic changes. There is marked proliferation of adipose tissue in the renal sinus, with...
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References and Further Reading

  1. Ratkal, V., Chawla, A., Mishra, D. K., & Krishna, S. (2015). Renal replacement lipomatosis of the right kidney. BML Case Reports, 6, 2015.Google Scholar
  2. Rha, S. E., Byun, J. Y., Jung, S. E., Oh, S. N., Choi, Y. J., Lee, A., & Lee, J. M. (2004). The renal sinus: Pathologic spectrum and multimodality imaging approach. Radiographics, 24(Suppl 1), S117–S131.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Institute of Pathological Anatomy and HistopathologyPolytechnic University of the Marche Region (Ancona), United Hospitals AnconaAnconaItaly