Renal Collecting Duct Carcinoma
- 2 Downloads
Bellini duct carcinoma
A highly malignant neoplasm arising from the principal cells of the renal collecting ducts of Bellini.
Collecting duct carcinoma is a rare tumor accounting for 1–2% of renal neoplasms.
It occurs in a wide age range with the median age similar to the other renal carcinoma.
There is a slight male predominance.
The tumor is centered on the renal medulla.
Radical nephrectomy is the standard of care, often with local lymphadenectomy. Since metastases are frequently present at the moment of the diagnosis, the surgical excision is followed by chemotherapy.
Frequently the patients are symptomatic, with lymph node involvement and metastases to the lungs, liver, bone, adrenals, and brain at the time of diagnosis.
They are usually large and infiltrative, whitish, and firm tumors grossly located in the medulla or central parts of the kidney (Fleming and Lewi 1986).
References and Further Reading
- Gupta, R., Billis, A., Shah, R. B., et al. (2012). Carcinoma of the collecting ducts of Bellini and renal medullary carcinoma: Clinicopathologic analysis of 52 cases of rare aggressive subtypes of renal cell carcinoma with a focus on their interrelationship. The American Journal of Surgical Pathology, 36, 1265–1278.PubMedCrossRefGoogle Scholar