Skip to main content

Dynamics of Disease States: Overview

Encyclopedia of Computational Neuroscience
  • 10 Accesses

Synonyms

Dynamical diseases; Periodic diseases

Definition

Computational neuroscience provides insights into the mechanisms that underlie dynamic diseases of the nervous system. Neuro-computationally inspired therapeutic devices that replace functions lost due to disease offer tangible hope to many for a better life.

Detailed Description

The evolution of an illness is one of the clues that a physician uses to arrive at a diagnosis and treatment strategy for diseases that affect the nervous system. Is the onset of the illness acute or subacute? Is the clinical course self-limited, relapsing-remitting, cyclic, chronic, and progressive? The impetus for studying disease dynamics comes from the mathematics and physics communities: their long experience has shown that insights into mechanism often derive from examining how dynamics change. Consequently the time evolution of a disease is modeled using differential equations, and disease processes are described in terms of the stability and...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  • Erdi P, Bhattacharya BS, Cochran AL (eds) (2017) Computational neurology and psychiatry. Springer, New York

    Google Scholar 

  • Jirsa VK, Proix T, Perdikis D, Woodman MM, Wang H, Gonzalez-Martinez J, Bernard C, Bénar C, Guye M, Chauvel P, Bartolomei F (2017) The virtual patient: individualized whole-brain models. NeuroImage 145:377–388

    Article  CAS  Google Scholar 

  • Lipsitz L, Lough M, Niemi J, Travison T, Howlett H, Manor B (2015) A shoe insole delivery subsensory vibration noise improves balance and gait in healthy elderly people. Arch Phys Med Rehabil 96:423–439

    Article  Google Scholar 

  • Mackey MC, Glass L (1977) Oscillation and chaos in physiological control systems. Science 197:287–289

    Article  CAS  Google Scholar 

  • Rao RPN, Stucco A, Bryan M, Sarma D, Youngquist TM, Wu J, Prat CS (2014) A direct brain-to-brain interface in humans. PLoS One 9:elll332

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to John Milton .

Editor information

Editors and Affiliations

Section Editor information

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Science+Business Media, LLC, part of Springer Nature

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Milton, J. (2020). Dynamics of Disease States: Overview. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_781-3

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_781-3

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-7320-6

  • Online ISBN: 978-1-4614-7320-6

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

Publish with us

Policies and ethics

Chapter history

  1. Latest

    Dynamics of Disease States: Overview
    Published:
    14 July 2020

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_781-4

  2. Dynamics of Disease States: Overview
    Published:
    12 February 2020

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_781-3

  3. Dynamics of Disease States: Overview
    Published:
    19 August 2014

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_781-2

  4. Original

    Dynamics of Disease States: Overview
    Published:
    27 May 2014

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_781-1