Dynamics of Disease States: Overview
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Computational neuroscience provides insights into the mechanisms that underlie dynamic diseases of the nervous system. Neuro-computationally inspired therapeutic devices that replace functions lost due to disease offer tangible hope to many for a better life.
The evolution of an illness is one of the clues that a physician uses to arrive at a diagnosis and treatment strategy for diseases that affect the nervous system. Is the onset of the illness acute or subacute? Is the clinical course self-limited, relapsing-remitting, cyclic, chronic, and progressive? The impetus for studying disease dynamics comes from the mathematics and physics communities: their long experience has shown that insights into mechanism often derive from examining how dynamics change. Consequently the time evolution of a disease is modeled using differential equations, and disease processes are described in terms of the stability and...