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Carnosine

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  • First Online:
Encyclopedia of Autism Spectrum Disorders

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Synonyms

beta-Alanyl-L-histidine

Definition

Carnosine is a compound formed from two amino acids (histidine and alanine) and is found in several organ systems including muscle and brain. A number of possible biological roles for this compound have been suggested including antioxidant properties. It has been used experimentally in several disorders. One small double-blind study in 2002 by Chez and colleagues reported positive initial findings, although the study was criticized on various grounds and the results have not yet been well replicated in the scientific literature.

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References and Reading

  • Chez, M. G., Buchanan, C. P., Aimonovitch, M. C., Becker, M., Schaefer, K., Black, C., & Komen, J. (2002). Double-blind, placebo-controlled study of L-carnosine supplementation in children with autistic spectrum disorders. Journal of Child Neurology, 17(11), 833–837.

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  • Levy, S. E., & Hyman, S. L. (2005). Novel treatments for autistic spectrum disorders. Mental Retardation and Developmental Disabilities Research Reviews, 11(2), 131–142.

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Authors and Affiliations

  1. Child Study Center, Irving B. Harris Professor of Child Psychiatry, Pediatrics and Psychology, Yale University School of Medicine, New Haven, CT, USA

    Fred R. Volkmar

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  1. Fred R. Volkmar
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Correspondence to Fred R. Volkmar .

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Editors and Affiliations

  1. Yale Child Study Center, New Haven, CT, USA

    Fred R. Volkmar

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Volkmar, F.R. (2020). Carnosine. In: Volkmar, F. (eds) Encyclopedia of Autism Spectrum Disorders. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6435-8_1384-3

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  • DOI: https://doi.org/10.1007/978-1-4614-6435-8_1384-3

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-6435-8

  • Online ISBN: 978-1-4614-6435-8

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