Encyclopedia of Autism Spectrum Disorders

Living Edition
| Editors: Fred R. Volkmar


  • Fred R. VolkmarEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6435-8_1384-3



Carnosine is a compound formed from two amino acids (histidine and alanine) and is found in several organ systems including muscle and brain. A number of possible biological roles for this compound have been suggested including antioxidant properties. It has been used experimentally in several disorders. One small double-blind study in 2002 by Chez and colleagues reported positive initial findings, although the study was criticized on various grounds and the results have not yet been well replicated in the scientific literature.

See Also

References and Reading

  1. Chez, M. G., Buchanan, C. P., Aimonovitch, M. C., Becker, M., Schaefer, K., Black, C., & Komen, J. (2002). Double-blind, placebo-controlled study of L-carnosine supplementation in children with autistic spectrum disorders. Journal of Child Neurology, 17(11), 833–837.CrossRefGoogle Scholar
  2. Levy, S. E., & Hyman, S. L. (2005). Novel treatments for autistic spectrum disorders. Mental Retardation and Developmental Disabilities Research Reviews, 11(2), 131–142.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2020

Authors and Affiliations

  1. 1.Child Study Center, Irving B. Harris Professor of Child Psychiatry, Pediatrics and PsychologyYale University School of MedicineNew HavenUSA