Encyclopedia of Autism Spectrum Disorders

Living Edition
| Editors: Fred R. Volkmar

Inferior Parietal Area

  • Jonathan KopelEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6435-8_102079-1



Autism spectrum disorder (ASD) is characterized by altered connectivity in cortical regions, such as the inferior parietal lobe, involved with communication and emotion regulation (Hanaie et al. 2016). The inferior parietal lobe integrates sensory and motor information to generate spatiotemporal representations (Hanaie et al. 2016). Among ASD patients, several studies have shown reduced gray matter and cortex in the inferior parietal lobe (Brieber et al. 2007; Wallace et al. 2010). Furthermore, these studies suggest that cortical thinning of the parietal and temporal cortices results from abnormal cortical growth in ASD patients (Wallace et al. 2010). Further research is required to elucidate the atypical neural growth and developmental mechanisms observed in ASD patients.

See Also

References and Reading

  1. Brieber, S., Neufang, S., Bruning, N., Kamp-Becker, I., Remschmidt, H., Herpertz-Dahlmann, B., et al. (2007). Structural brain abnormalities in adolescents with autism spectrum disorder and patients with attention deficit/hyperactivity disorder. Journal of Child Psychology and Psychiatry, 48(12), 1251–1258.  https://doi.org/10.1111/j.1469-7610.2007.01799.x.CrossRefPubMedGoogle Scholar
  2. Hanaie, R., Mohri, I., Kagitani-Shimono, K., Tachibana, M., Matsuzaki, J., Hirata, I., et al. (2016). White matter volume in the brainstem and inferior parietal lobule is related to motor performance in children with autism spectrum disorder: A voxel-based morphometry study. Autism Research, 9(9), 981–992.  https://doi.org/10.1002/aur.1605.CrossRefPubMedGoogle Scholar
  3. Wallace, G. L., Dankner, N., Kenworthy, L., Giedd, J. N., & Martin, A. (2010). Age-related temporal and parietal cortical thinning in autism spectrum disorders. Brain, 133(12), 3745–3754.  https://doi.org/10.1093/brain/awq279.CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Texas Tech University Health Sciences Center (TTUHSC)LubbockUSA