‡This chapter was reprinted from the first edition of the Springer Index of Viruses. Taxonomy and classification of the virus species described in this chapter may have changed.
You have full access to this open access chapter, Download reference work entry PDF
Virion
Morphology: | Spherical |
Envelope: | Yes |
Diameter (nm): | 120–160 |
Length (nm): | |
Structural components: | Nucleocapsid, core, envelope |
Buoyant density (g/mL): | 1.23–1.24 |
Buoyant density method: | CsCl |
Lipid composition: | Envelope lipids are derived from cytoplasma membrane of host cell |
Additional information: |
Genome
Nucleic acid: | RNA | |
Strandedness: | ||
Polarity: | ||
Configuration: | ||
Segment organization: | 0 segment(s): | (kb) total (calculated) |
G + C content (%): | Unknown | |
mRNA transcripts: | Unknown | |
Open reading frames: | Unknown | |
Additional information: |
Replication
Entry mechanism: | Receptor-mediated endocytosis |
Site of transcription: | Cytoplasm |
Transcriptase: | Virus-encoded RNA-dependent RNA polymerase |
Site of genome replication: | Cytoplasm |
Replicase: | Virus-encoded RNA-dependent RNA polymerase |
Replication intermediate: | Negative-strand RNA intermediate |
Site of virion assembly: | Cytoplasm, the intermediate compartment |
Egress mechanism: | Unknown |
Additional information: |
History
Year of event | Event | References |
---|---|---|
1979 | Coronavirus-like particles identified in rabbits with cardiomyopathy | Small et al (1979) |
1980 | Coronavirus-like particles identified in teh intestine of laboratory rabbits | Lapierre et al (1980) |
1987 | Serological relatedness demonstrated between RbCoV and human coronaviruses | Small, Woods (1987) |
1992 | RbCoV established as animal model for dilated cardiomyopathy | Alexander et al (1992) |
Genus Members
Species name | Synonyms | Wild-type strains/isolates | Natural host range | Experimental host range | Membership status |
---|---|---|---|---|---|
Rabbit coronavirus (RbCoV) | European rabbits (Oryctolagus cuniculus) | Unassigned |
Biology
Species | Permissive cell lines | Tissue tropism | Cytopathic effects | Additional information |
---|---|---|---|---|
RbCoV | Intestinal epithelium, myocardium | Haemagglutinates rabbit red blood cells |
Diseases
Disease | Causative agent | Affected organisms | Disease characteristics | Transmission route/vector | Treatment | Geographic distribution |
---|---|---|---|---|---|---|
Rabbit infectious cardiomyopathy | RbCoV | Rabbits | Enteritis, myocarditis, dilated cardiomyopathy and congestive heart failure | Faecal-oral | Canada, Europe |
Diagnosis
Method | Species | Sample material | Detection target | References |
---|---|---|---|---|
Electron or immunoelectron microscopy | RbCoV | Faeces, tissue (heart) samples | Particle morphology | Descôteaux et al (1983) |
References
Edwards et al (1992)
Edwards et al (1992)
Lapierre et al (1980)
Small et al (1987)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer Science+Business Media, LLC
About this entry
Cite this entry
Decaro, N. (2011). Rabbit Coronavirus-like Viruses‡. In: Tidona, C., Darai, G. (eds) The Springer Index of Viruses. Springer, New York, NY. https://doi.org/10.1007/978-0-387-95919-1_59
Download citation
DOI: https://doi.org/10.1007/978-0-387-95919-1_59
Publisher Name: Springer, New York, NY
Print ISBN: 978-0-387-95918-4
Online ISBN: 978-0-387-95919-1
eBook Packages: Biomedical and Life SciencesReference Module Biomedical and Life Sciences