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Protein Self-Assembly: Strategies and Applications

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Handbook of Macrocyclic Supramolecular Assembly

Abstract

As intriguing biomacromolecules with a vast array of biodiversity and functions, proteins are well-known essential building blocks of organisms and participate in every process of cells such as metabolism, gene transcription and expression, stimuli response, and molecule transportation. However, virtually, organisms could systematically execute most important biological functions in the form of complex hierarchical complex hierarchical structures and collective properties of protein assembly. Therefore, the protein assemblies are compelling for scientists to not only understand the sophisticated, synergistic, and highly functional process of natural life but also provide a fascinating access to prepare advanced biomaterials. In decades, deep cognition of natural protein assemblies and complex has been made, which offers people a glimpse of the altruistic behaviors happen in nature and human bodies. In the meantime, there have been undergoing unexpected and rapid developments in protein assembly field using supramolecular interaction as driven forces, and various innovative design and strategies have been emerging to construct intriguing biomaterials. This chapter proposes to lead the reader to appreciate the splendid natural protein architecture, introduce the recent advances in the research field of protein assembly, and highlight several innovative design strategies for precise manipulation of proteins into extended, periodic arrays with desired morphologies and applications.

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Authors and Affiliations

  1. Department of Chemistry, Jilin University, Changchun, China

    Shanpeng Qiao & Junqiu Liu

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  1. Shanpeng Qiao
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  2. Junqiu Liu
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Correspondence to Junqiu Liu .

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Editors and Affiliations

  1. College of Chemistry, Nankai University College of Chemistry, Tianjin, Tianjin, China

    Yu Liu

  2. College of Chemistry, Nankai University College of Chemistry, Tianjin, Tianjin, China

    Yong Chen

  3. College of Chemistry, Nankai University College of Chemistry, Tianjin, Tianjin, China

    Heng-Yi Zhang

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Qiao, S., Liu, J. (2019). Protein Self-Assembly: Strategies and Applications. In: Liu, Y., Chen, Y., Zhang, HY. (eds) Handbook of Macrocyclic Supramolecular Assembly . Springer, Singapore. https://doi.org/10.1007/978-981-13-1744-6_38-1

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  • DOI: https://doi.org/10.1007/978-981-13-1744-6_38-1

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  • Print ISBN: 978-981-13-1744-6

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