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Ionic Liquids for Anticancer Application

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Encyclopedia of Ionic Liquids

Synonyms

Antitumor agents

Introduction

Cancer is a serious life-threatening and/or chronic disease with a considerable social and economic impact on a global scale. The World Health Organization reports for 18.1 million newly registered cancer patients and 9.6 million cancer deaths in 2018 (https://www.who.int/cancer/PRGlobocanFinal.pdf). While searching for innovative and effective anticancer drugs, researchers have focused their attention on ionic liquids (ILs) as potential anticancer therapeutics. ILs are compounds composed of large organic cations and organic or inorganic anions [1]. In general, they are characterized with low melting points (below 100 °C), low volatility, and high-temperature stability [1]. Their chemical structure can be easily modified; therefore their physicochemical properties and biological activities are easily tunable. ILs are synthesized via reactions of neutralization or metatheses [1].

Cellular toxicity is a complex process involving multiple pathways,...

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Authors and Affiliations

  1. Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria

    Maya Guncheva

Authors
  1. Maya Guncheva
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Correspondence to Maya Guncheva .

Editor information

Editors and Affiliations

  1. Institute of Process Engineering, Chinese Academy of Science, Institute of Process Engineering, Beijing, China

    Suojiang Zhang

Section Editor information

  1. Key Laboratory of Colloid and Interface Chemistry, Ministry of Education, Shandong University, Jinan, China

    Zhonghao Li

  2. Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria

    Maya Guncheva

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Guncheva, M. (2019). Ionic Liquids for Anticancer Application. In: Zhang, S. (eds) Encyclopedia of Ionic Liquids. Springer, Singapore. https://doi.org/10.1007/978-981-10-6739-6_6-1

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  • DOI: https://doi.org/10.1007/978-981-10-6739-6_6-1

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-6739-6

  • Online ISBN: 978-981-10-6739-6

  • eBook Packages: Springer Reference Chemistry and Mat. ScienceReference Module Physical and Materials ScienceReference Module Chemistry, Materials and Physics

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