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Kinderchirurgie pp 1–7Cite as

Non-Hodgkin-Lymphome bei Kindern und Jugendlichen

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Part of the book series: Springer Reference Medizin ((SRM))

Zusammenfassung

Die Non-Hodgkin-Lymphome (NHL) stellen eine heterogene Gruppe von bösartigen Erkrankungen des lymphatischen Systems dar und umfassen alle bösartigen Lymphome, die keine Hodgkin-Lymphome sind. Sie sind im Kindes- und Jugendalter hoch aggressiv und schnell wachsend. Die relative Häufigkeit in Deutschland beträgt 6,2 % aller Tumorerkrankungen im Kindesalter. Typische Vertreter sind die Burkitt-Lymphome inkl. der reifzelligen B-Zelltyp-Leukämien, die T- und B-lymphoblastischen Lymphome sowie die großzellig anaplastischen Lymphome. Die klinische Symptomatik ist heterogen und reicht von der schmerzlosen Lymphadenopathie, über das akute Abdomen, pulmonale Symptome bei mediastinalem Tumorbefall, ZNS-Symptome bis hin zur Zytopenie bei Knochenmarkbeteiligung. Die Diagnosesicherung erfolgt histologisch. Die Behandlung erfolgt mittels Zytostatika. Die chirurgische Therapie ist abdominellen Notfallsituationen vorbehalten. Die Prognose ist insgesamt gut.

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Author information

Authors and Affiliations

  1. Klinik für Kinderchirurgie, Universitätsklinikum Gießen/Marburg, Marburg, Deutschland

    Guido Seitz

  2. Abt. für Pädiatrische Hämatologie/Onkologie, Universitätsklinikum Gießen/Marburg, Gießen, Deutschland

    Christine Mauz-Körholz

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  1. Guido Seitz
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  2. Christine Mauz-Körholz
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Correspondence to Guido Seitz .

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Editors and Affiliations

  1. Kinderchirurgische Klinik und Poliklinik, Klinikum der Universität München Kinderchirurgische Klinik und Poliklinik, München, Bayern, Germany

    Dietrich von Schweinitz

  2. Abt. Kinderchirurgie, Medizinische Hochschule Hannover (MHH) Kinderklinik, Hannover, Germany

    Benno Ure

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Seitz, G., Mauz-Körholz, C. (2018). Non-Hodgkin-Lymphome bei Kindern und Jugendlichen. In: von Schweinitz, D., Ure, B. (eds) Kinderchirurgie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-53390-1_92-1

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  • DOI: https://doi.org/10.1007/978-3-662-53390-1_92-1

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