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Praktische Schmerzmedizin pp 1–13Cite as

Zerebrale Mechanismen – Bildgebung (Schmerzmatrix – Schmerznetzwerk)

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Part of the book series: Springer Reference Medizin ((SRM))

Zusammenfassung

Der Einsatz funktioneller Bildgebungsverfahren zur Untersuchung experimenteller und klinischer Schmerzzustände hat in der Vergangenheit maßgeblich zum Verständnis neuronaler Prozesse und deren Lokalisation im Gehirn beigetragen. Vor der Entwicklung dieser Verfahren basierte unser Wissen über die Schmerzverarbeitung bzw. die funktionelle Anatomie v. a. auf molekularbiologischen und elektrophysiologischen Befunden (Penfield und Boldrey (1937) Somatic motor and sensory representation in the cerebral cortex of man as studied by electrical stimulation. Brain 60:389–443; Stowell (1984) Event related brain Potenzials and human pain: a first objective overview. Int J Psychophysiol 1:137–151), Tierversuchen und Läsionsstudien (Head und Holmes (1911) Sensory disturbances from cerebral lesions. Brain 34:102–254; Folz und White (1962) Pain ‚relief‘ by frontal cingulumotomy. J Neurosurg 19:89–100; Berthier et al. (1988) Asymbolia for pain: a sensory-limbic disconnection syndrome. Ann Neurol 24:41–49). Im Gegensatz dazu stehen heute mit den modernen bildgebenden Verfahren Instrumente zur Verfügung, die nichtinvasive Untersuchungen in vivo und bei vollem Bewusstsein erlauben. Diese Techniken ermöglichen völlig neue Einblicke in die Schmerzverarbeitung, die zeitliche Dynamik sowie die Modulation.

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Authors and Affiliations

  1. Neurologische Klinik und Poliklinik der Technischen Universität München, Klinikum rechts der Isar, Ismaninger Str. 22, München, 81675, Deutschland

    Anne Stankewitz & Thomas R. Tölle

  2. Neurologisch-Neurochirurgische Poliklinik und Abteilung für Neuroradiologie, Universitätsspital Basel, Petersgraben 4, Basel, 4031, Schweiz

    Till Sprenger

  3. Benedictus Krankenhaus Feldafing, Dr.-Appelhans-Weg 6, Feldafing, 82340, Deutschland

    Michael Valet

Authors
  1. Anne Stankewitz
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  2. Till Sprenger
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  3. Michael Valet
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  4. Thomas R. Tölle
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Correspondence to Anne Stankewitz .

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Editors and Affiliations

  1. Klinik für Neurologie, Universitätsklinikum Kiel, Kiel, Germany

    Ralf Baron

  2. Klinik für Anästhesiologie und Intensivmedizin, Medizinische Hochschule Hannover, Hannover, Germany

    Wolfgang Koppert

  3. Göttingen, Germany

    Michael Strumpf

  4. Klinik für Anästhesiologie, Universitätsmedizin Göttingen, Göttingen, Germany

    Anne Willweber-Strumpf

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Stankewitz, A., Sprenger, T., Valet, M., Tölle, T.R. (2018). Zerebrale Mechanismen – Bildgebung (Schmerzmatrix – Schmerznetzwerk). In: Baron, R., Koppert, W., Strumpf, M., Willweber-Strumpf, A. (eds) Praktische Schmerzmedizin. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54670-9_11-2

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  • DOI: https://doi.org/10.1007/978-3-642-54670-9_11-2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-54670-9

  • Online ISBN: 978-3-642-54670-9

  • eBook Packages: Springer Referenz Medizin

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Chapter history

  1. Latest

    Zerebrale Mechanismen – Bildgebung (Schmerzmatrix – Schmerznetzwerk)
    Published:
    15 December 2017

    DOI: https://doi.org/10.1007/978-3-642-54670-9_11-2

  2. Original

    Funktionelle Bildgebung bei Schmerz
    Published:
    08 November 2014

    DOI: https://doi.org/10.1007/978-3-642-54670-9_11-1

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