Abstract
Sesame is a valuable oilseed crop that contains various nutritionally rich bioactive compounds including lignans, tocopherol homologues, phytosterols, etc. Lignans are the product of oxidative coupling of β-hydroxyphenylpropane. Sesame has a combination of glycosylated lignans and oil-dispersed lignans. Based on their medicinal and pharmacological properties, the most important lignans are sesamin, sesamol, sesamolin, and sesaminol. Tocopherols (vitamin E compounds) are the lipid-soluble free radicals and constitute a major part of human diet. In sesame seeds, α-, γ-, and δ-tocopherols are found as tocopherol homologues. In addition to lignans and tocopherols, sesame is an important source of phytosterols, phytates, polyunsaturated fatty acids, and bioactive peptides. However, utilization potential of many of these compounds has not yet been fully understood. This chapter delves into the presence of multifarious bioactive components in sesame seeds, their biosynthetic pathway, and functional importance.
This is a preview of subscription content, log in via an institution.
Abbreviations
- CYP81Q1:
-
Sesamin synthase
- DIR1:
-
Dirigent protein
- DMPQ:
-
2,3-Dimethyl-5-phytyl-1,4-hydroquinol
- VTE1:
-
Tocopherol cyclase
- γ-TMT:
-
γ-Tocopherol methyltransferase
References
Ashri A (2007) Sesame (Sesamum indium L.) In: Singh RJ (ed) Genetic resources, chromosome engineering, and crop improvement, Oilseed crops, vol 4. CRC Press, Boca Raton, pp 231–289
Joshi AB (1961) Sesamum. Indian Central Oilseed Committee, Hyderabad, pp 1–109
Weiss EA (1971) Sesame, castor and safflower, barnes and noble, World crop series. Leonard Hill, New York, pp 311–525
Bedigian D, Seihler DS, Harlan JR (1985) Sesamin, sesamolin and the origin of sesame. Biochem Syst Ecol 13:133–139
Bedigian D, Harlan JR (1986) Evidence for cultivation of sesame in the ancient world. Econ Bot 40:137–154
USDA (2015) USDA national nutrient database for standard reference, release 18. U.S. Department of Agriculture, Agricultural Research Service, Nutrient Data Laboratory, Beltsville. http://www.nal.usda.gov/fnic/foodcomp
Pathak N, Rai AK, Ratna K, Bhat KV (2014) Value addition in sesame: a perspective on bioactive components for enhancing utility and profitability. Pharmacogn Rev 8(16):147–155. https://doi.org/10.4103/0973-7847.134249
Dimitrios B (2006) Sources of natural phenol antioxidants. Trends Food Sci Technol 17:505–512
Manach C, Williamson G, Morand C, Scalbert A, Remesy C (2005) Bioavailability and bioefficacy of polyphenols in humans I- review of 97 bioavailability studies. Am J Clin Nutr 81:230S–242S
Temple NJ (2000) Antioxidants and disease: more questions than answers. Nutr Res 20:449–559
Kamal-Eldin A, Appelquist LA, Yousif G (1994) Lignan analysis in seed oils from four sesamum species: comparison of different chromatographic methods. J Am Oil Chem Soc 71:141–145
Robinson R (1927) The relationship of some complex natural products to the simple sugars and amino acids. Durham Univ Philos Soc 8:14–59
Haworth RD (1936) Natural resins. Annu Rep Progr Chem 33:266–279
Katsuzaki H, Osawa T, Kawakishi S (1994) Chemistry and antioxidative activity of lignan glucosides in sesame seed. ACS Symp Ser 574:275–280
Katsuzaki H, Osawa T, Kawashiki S (1994) Chemistry and antioxidative activity of lignan glucosides in sesame seed, Chapter 28. In: Food phytochemicals for cancer prevention, ACS symposium series, vol 547. American Chemical Society, Washington, DC, pp 275–280
Moazzami AA, Andersson RE, Kamal-Eldin A (2006) HPLC analysis of sesaminol glucosides in sesame seeds. J Agric Food Chem 54:633–638. https://doi.org/10.1021/jf051541g
Brar G, Ahuja KL (1979) Sesame: its culture, genetics, breeding and biochemistry. Annu Rev Plant Sci 1:245–313
Yamashita K, Iizuka Y, Imai T, Namiki M (1995) Sesame seed and its lignans produce marked enhancement of vitamin E activity in rats fed a low alpha- tocopherol diet. Lipids 30:1019–1028
Namiki M (1995) The chemistry and physiological functions of sesame. Food Rev Int 11: 281–329
Kamal-Eldin A (2005) Minor components in vegetable oils. In: Shahidi F (ed) Baileys industrial fats and oils. Chapter 12, edible oil and fat products: speciality oils and oil products. Wiley, Sussex
Haller HL, Mc Govran ER, Goodhue LD, Sullivan WN (1942) The synergistic action of sesamin with pyrethrum insecticides. J Org Chem 7(2):183–184
Jones WA, Beroza M, Decker ED (1962) Isolation and structure of sesangolin: a constituent of Sesamum angolense. J Org Chem 27:3232–3235
Cassida JE, Engel JL, Essac EG, Kamienski FX, Kuwatsuka S (1966) Methylene-14C-dioxyphenyl compounds: metabolism in relation to their synergistic action. Science 153:1130–1133
Mathews CK, Van Holde KE, Ahern KG (2000) Biochemistry, 3rd edn, Benjamin/Cummings, an imprint of Addison Wesley Longman, pp 700–704
Jain SC, Khanna P (1973) Production of sterols from Sesamum indicum L. tissue culture. Indian J Pharm 35:163–164
Kato MJ, Chu A, Davin LB, Lewis NG (1998) Biosynthesis of antioxidant lignans in Sesamum indicum seeds. Phytochemistry 47(4):583–591
Davin LB, Wang HB, Crowell AL, Bedgar DL, Martin DM, Sarkanen S, Lewis NG (1997) Stereoselective bimolecular phenoxy radical coupling by an auxiliary (dirigent) protein without an active center. Science 275:362–366
Jiao Y, Davin LB, Lewis NG (1998) Furanofuran lignan metabolism as a function of seed maturation in Sesamum indicum: methylenedioxy bridge formation. Phytochemistry 49:387–394
Ono E, Nakai M, Fukui Y, Tomimori N, Fukuchi-Mizutani M, Saito M, Satake H, Tanaka T, Katsuta M, Umezawa T, Tanaka Y (2006) Formation of two methylenedioxy bridges by a Sesamum CYP81Q protein yielding a furofuran lignan, (+)-sesamin. Proc Natl Acad Sci USA 103(26):10116–10121
Yoshida Y, Niki E, Noguchi N (2003) Comparative study on the action of tocopherols and tocotrienols as antioxidant: chemical and physical effects. Chem Phys Lipids 123(1):63–75
Hofius D, Sonnewald U (2003) Vitamin E biosynthesis: biochemistry meets cell biology. Trends Plant Sci 8(1):6–8
Brigelius-Flohe R, Traber MG (1999) Vitamin E: function and metabolism. FASEB J 13(10): 1145–1155
Colombo ML (2010) An update on vitamin E, tocopherol and tocotrienol- perspectives. Molecules 15(4):2103–2113. https://doi.org/10.3390/molecules15042103
Bramley PM, Elmadfa I, Kafatos A, Kelly FJ, Manios Y, Rexborough HE, Schuch W, Sheehy PJA, Wagner KH (2000) Vitamin E. J Sci Food Agric 80:913–938
Herbers K (2003) Vitamin production in transgenic plants. J Plant Physiol 160:821–829. https://doi.org/10.1078/0176-1617-01024
Franzen JJ, Bausch D, Glatze D, Wagner E (1991) Distribution of vitamin E in spruce seedling and mature tree organs, and within the genus. Phytochemistry 30:147–151
Hassapidou MN, Manoukas AG (1993) Tocopherol and tocotrienol compositions of raw table olive fruit. J Sci Food Agric 61(2):277–280
DellaPenna (2005) Progress in the dissection and manipulation of vitamin E synthesis. Trends Plant Sci 10:574–579. https://doi.org/10.1016/j.tplants.2005.10.007
Norris SR, Shen X, DellaPenna D (1998) Complementation of the Arabidopsis pds1 mutation with the gene encoding p-hydroxyphenylpyruvate dioxygenase. Plant Physiol 117:1317–1323
Collakova E, DellaPenna D (2001) Isolation and functional analysis of homogentisate phytyltransferase from Synechocystis sp. PCC 6803 and Arabidopsis. Plant Physiol 127:1113–1124
Savidge B, Weiss JD, Wong YHH, Lassner MW, Mitsky TA, Shewmaker CK, Beittenmiller D, Valentin HE (2002) Isolation and characterization of homogentisate phytyltransferase genes from Synechocystis sp. PCC 6803 and Arabidopsis. Plant Physiol 129:321–322
Cheng Z, Sattler S, Maeda H, Sakuragi Y, Bryant DA, Dellapenna D (2003) Highly divergent methyltransferases catalyze a conserved reaction in tocopherol and plastoquinone synthesis in cyanobacteria and photosynthetic eukaryotes. Plant Cell 15:2343–2356
Van Eenennaam AL, Lincoln K, Durett TP, Valentin HE, Shewmaker CK, Thorne GM, Jiang J, Baszis SR, Levering CK, Aasen ED, Hao M, Stein JC (2003) Engineering vitamin E content: from Arabidopsis mutant to soy oil. Plant Cell 15(12):3007–3019
Porfirova S, Bergmüller E, Tropf S, Lemke R, Dörmann P (2002) Isolation of an Arabidopsis mutant lacking vitamin E and identification of a cyclase essential for all tocopherol biosynthesis. Proc Natl Acad Sci U S A 99:12495–12500
Sattler SE, Cajon EB, Coughlin SJ, DellaPenna D (2003) Characterization of tocopherol cyclases from higher plants and cyanobacteria: evolutionary implications for tocopherol synthesis and function. Plant Physiol 132:2184–2195
Budowski P, Markley KS (1951) The chemical and physiological properties of sesame oil. Chem Rev 48:125–151
Osawa T, Nagata M, Namiki M, Fukuda Y (1985) Sesamolinol, a novel antioxidant isolated from sesame seeds. Agric Biol Chem 49:3351–3352
Hirata F, Fujita K, Ishikura Y, Hosoda K, Ishikawa T, Nakamura H (1996) Hypercholesterolemic effect of sesame lignan in human. Atherosclerosis 122:135–136
Shimizu S, Akimoto K, Shinmen Y, Kawashima H, Sugano M, Yamada H (1991) Sesamin is a potent and specific inhibitor of delta-5-desaturase in polyunsaturated fatty acid biosynthesis. Lipids 26:512–516
Hirose N, Inoue T, Nishihara K, Sugano M, Akimoto K, Shimizu S, Yamada S (1991) Inhibition of cholesterol absorption and synthesis in rats by sesamin. J Lipid Res 32:629–638
Yokota T, Matsuzaki Y, Koyama M, Hitomi T, Kawanaka M, Enoki-Konish M, Okuyama Y, Takayasu J, Nishino H, Nishikawa A, Osawa T, Sakai T (2007) Sesamin, a lignan of sesame, down-regulates cyclin D1 protein expression in human tumor cells. Cancer Sci 98(9): 1447–1453. https://doi.org/10.1111/j.1349-7006.2007.00560.x
Hsu DZ (2005) Effect of sesame oil on oxidative-stress-associated renal injury in endotoxemic rats: involvement of nitric oxide and proinflammatory cytokines. Shock 24:276–280
Ashakumary L, Rouyer I, Takahashi Y, Ide T, Fukuda N, Aoyama T, Hashimoto T, Mizugaki M, Sugano M (1999) Sesamin, a sesame lignan, is a potent inducer of hepatic fatty acid oxidation in the rat. Metabolism 48:1303–1313
Nonaka M, Yamashita K, Izuka Y, Namiki M (1997) Effects of sesaminol and sesamin on eicosanoid production and immunoglobulin level in rats given ethanol. Biosci Biotechnol Biochem 61:836–839
Lee CC, Chen PR, Lin S, Tsai SC, Wang BW, Chen WW (2004) Sesamin induces nitric oxide and decreases endothelin-1 production in HUVECs: possible implications for its antihypertensive effect. J Hypertens 22:2329–2338
Nakano D, Kurumazuka D, Nagai Y, Nishiyama A, Kiso Y, Matsumura Y (2008) Dietary sesamin suppresses aortic NADPH oxidase in DOCA salt hypertensive rats. Clin Exp Pharmacol Physiol 35(3):324–326. https://doi.org/10.1111/j.1440-1681.2007.04817.x
Cheng FC, Jinn TR, Hou RC, Tzen JTC (2006) Neuroprotective effects of sesamin and sesamolin on gerbil brain in cerebral ischemia. Int J Biomed Sci 2(3):284–288
Hemalatha S, Ghafoorunissa (2004) Lignans and tocopherols in Indian sesame cultivars. J Am Oil Chem Soc 81:467–470
Abe C, Ikeda S, Yamashina K (2005) Dietary sesame seeds elevate α-tocopherol concentration in rat brain. J Nutr Sci Vitaminol 51:223–230
Kamal-Eldin A, Pettersson D, Appelqvist LÅ (1995) Sesamin (a compound from sesame oil) increases tocopherol levels in rats fed ad libitum. Lipids 30:499–505
Wu WH, Kang YP, Wang NH, Jou HJ, Wang TA (2006) Sesame ingestion affects sex hormones, antioxidant status, and blood lipids in postmenopausal women. J Nutr 136(5): 1270–1275
Mak DHF, Po YC, Kam MK (2011) Antioxidant and anti-carcinogenic potentials of sesame lignans. In: Bedigian D (ed) Sesame the genus sesamum. CRC Press, Boca Raton
Sandra MS, Lilian UT (2011) Sesame seeds and its lignans: metabolism and bioactivities. In: Bedigian D (ed) Sesame the genus Sesamum. CRC Press, Boca Raton
Matsumara Y, Kita S, Tanida Y, Taguchi S, Morimoto S, Akimoto K, Tanaka T (1998) Antihypertensive effect of sesamin, protection against development and maintenance of hypertension in stroke-prone spontaneously hypertensive rats. Biol Pharm Bull 21:469–473
Chavali SR, Zhong WW, Forse RA (1998) Dietary α-linolenic acid increases TNF-α, and decreases IL-6, IL-10 in response to LPS: effect of sesamin on the Δ-5 desaturation of ω6 and ω3 fatty acids in mice. Prostaglandins Leukot Essent Fat Acids 58(3):185–191
Lim JS, Adachi Y, Takahashi Y, Ide T (2007) Comparative analysis of sesame lignans (sesamin and sesamolin) in affecting hepatic fatty acid metabolism in rats. Br J Nutr 97(1):85–95. https://doi.org/10.1017/S0007114507252699
Sirato-Yasumoto S, Katsuta M, Okuyama Y, Takahashi Y, Ide T (2001) Effect of sesame seeds rich in sesamin and sesamolin on fatty acid oxidation in rat liver. J Agric Food Chem 49:2647–2651
Hirose N, Doi F, Ueki T, Akazawa K, Chijiiwa K (1992) Suppressive effect of sesamin against 7, 12-dimethylbenz[a]-anthracene induced rat mammary carcinogenesis. Anticancer Res 12:1259–1265
Coulman KD, Liu Z, Quan HW, Michaelides J, Thompson LU (2005) Whole sesame seed is as rich a source of mammalian lignan precursors as whole flaxseed. Nutr Cancer 52:156–165. https://doi.org/10.1207/s15327914nc5202_6
Liu Z, Saarinen NM, Thompson LU (2006) Sesamin is one of the major precursors of mammalian lignans in sesame seed (Sesamum indicum) as observed in vitro and in rats. J Nutr 136:906–912
Penalvo JL, Heinonen SM, Aura AM, Adlercreutz H (2005) Dietary sesamin is converted to enterolactone in humans. J Nutr 135:1056–1062
Annussek G (2001) Sesame oil in: gale encyclopedia of alternative medicine. Gale Group and Looksmart, Detroit
Ang ES, Lee ST, Gan CS, See PG, Chan YH, Nag LH, Machin D (2001) Evaluating the role of alternative therapy in burn wound management: randomized trial comparing moist exposed burn ointment with conventional methods in the management of patients with second- degree burns. Med Gen Med 3:2–7
Yong YL (1999) Analysis of MEBO cream, Report no. 99033191. Institute of Science and Forensic Medicine, Department of Scientific Services, Health Science Division, Singapore
Kamal-Eldin A, Appelqvist LÅ (1996) The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids 31:671–701
Burton GW, Traber MG (1990) Vitamin E in antioxidant activity biokinetics and bioavailability. Annu Rev Nutr 10:375–382. https://doi.org/10.1146/annurev.nu.10.070190.002041
Burton GW (1994) Vitamin E: molecular and biological function. Proc Nutr Soc 53(2): 251–262
Li D, Saldeen T, Romeo F, Mehta JL (1999) Relative effects of alpha- and gamma-tocopherol on low-density lipoprotein oxidation and superoxide dismutase and nitric oxide synthase activity and protein expression in rats. J Cardiovasc Pharmacol Ther 4:219–226
Saldeen T, Engström K, Jokela R, Wallin R (1999) Natural antioxidants and anticarcinogens in nutrition, health and disease. In: Importance of in vitro stability for in vivo effects of fish oils. The Royal Society of Chemistry, Cambridge, UK, Special Publication 240, pp 326–330
Qureshi AA, Bradlow BA, Brace L, Manganello J, Peterson DM, Pearce BC, Wright JJK, Gapor A, Elson CE (1995) Response of hypercholesterolemic subjects to administration of tocotrienols. Lipids 30(12):1171–1177
Schwenke DC (2002) Does lack of tocopherols and tocotrienols put women at increased risk of breast cancer? J Nutr Biochem 13(1):2–20
Olcott HS, Emerson OH (1937) Antioxidants and the autoxidation of fats, IX, the antioxidant properties of the tocopherols. J Am Oil Chem Soc 59(6):1008–1009
Girotti AW (1998) Lipid hydroperoxide generation, turnover, and effector action in biological systems. J Lipid Res 39:1529–1542
Liebler DC (1993) The role of metabolism in the antioxidant functions of vitamin E. Crit Rev Toxicol 23:147–169. https://doi.org/10.3109/10408449309117115
Dabrowski KJ, Sosulski F (1984) Quantification of free and hydrolizable phenolic acids in seeds by capillary gas liquid chromatography. J Agric Food Chem 32(1):123–127
Feroj-Hasan AFM, Begu S, Furumoto T, Fukui H (2000) A new chlorinated red napthaquinone from roots of Sesamum indicum. Biosci Biotechnol Biochem 64:873–874. https://doi.org/10.1271/bbb.64.873
Lyon CK (1972) Sesame, present knowledge of composition and use. J Am Oil Chem Soc 49:245–249
Shimoda T, Takabayashi J, Ashira W, Takafuji (1997) Response of predatory insect Scolothrips takahashi towards herbivore induced plant volatiles under laboratory and field conditions. J Chem Ecol 23:2033–2048
Salunkhe DK, Chavan JK, Adsule RN, Kadam SS (1991) World oilseeds: chemistry, technology and utilization. Springer, New York, pp 1–554
Van Rensburg SJ, Daniels WM, Van Zyl JM, Taljaard JJ (2000) A comparative study of the effects of cholesterol, beta-sitosterol, beta-sitosterol glucoside, dehydroepiandrosterone sulphate and melatonin on in vitro lipid peroxidation. Metab Brain Dis 15:257–265
Bouic PJ (2002) Sterols and sterolins: new drugs for the immune system? Drug Discov Today 7:775–778
Zhao W, Miao X, Jia S, Pan Y, Huang Y (2005) Isolation and characterization of microsatellite loci from the mulberry Morus L. Plant Sci 168:519–525
Moreau RA, Whitaker BD, Hicks Kevin B (2002) Phytosterols, phytostanols, and their conjugates in foods: structural diversity, quantitative analysis, and health-promoting uses. Prog Lipid Res 41:457–500
Mohamed HM, Awatif II (1998) The use of sesame oil unsaponifiable matter as a natural antioxidant. Food Chem 62:269–276
Gharby S, Harhar H, Bouzoubaa Z, Asdadi A, El Yadini A, Charrouf Z (2015) Chemical characterization and oxidative stability of seed and oil of sesame grown in Morocco. J Saudi Soc Agric Sci 16:105–111. https://doi.org/10.1016/j.jssas.2015.03.004
Pegel KH (1997) The importance of sitosterol and sitosterolin in human and animal nutrition. S Afr J Sci 93:263–268
Nieman DC (1994) Exercise, infection and immunity. Int J Sports Med 15:131–141. https://doi.org/10.1055/s-2007-1021128
de Boland AR, Garner GB, O’Dell BL (1975) Identification and properties of “phytate” in cereal grains and oilseed products. J Agric Food Chem 23:1186–1189
Graf E, Dintzis FR (1982) High-performance liquid chromatographic method for the determination of phytate. Anal Biochem 119:413–417
Urbano G, López-Jurado M, Aranda P, Vidal-Valverde C, Tenorio E, Porres J (2000) The role of phytic acid in legumes: antinutrient or beneficial function? J Physiol Biochem 56:283–294
Kuroda Y, Shamsuddin AM (1995) Inositol phosphates have novel anticancer function. J Nutr 125:725S–732S
Gunstone F, Harwood JL, Padley FB (1994) The lipid handbook, 2nd edn. Chapman and Hall, London, pp 47–208
Simopoulos AP (1999) Essential fatty acids in health and chronic disease. Am J Clin Nutr 70(3 Suppl):560S–569S
Kankaanpaa P, Sutas Y, Salminen S, Lichtenstein A, Isolauri E (1999) Dietary fatty acids and allergy. Ann Med 31:282–287
Kamal-Eldin A, Appelqvist LÅ (1994) Variation in the composition of sterols, tocopherols and lignans in seed oils from four Sesamum species. J Am Oil Chem Soc 71:149–156
Spencer GF, Herb SF, Gormisky PJ (1976) Fatty acid composition as a basis for identification of commercial fats and oils. J Am Oil Chem Soc 53:94–96
Shahidi F, Tan Z (2011) Physiological effects of sesame bioactive and antioxidant compounds. In: Bedigian D (ed) Sesame the genus sesamum. CRC Press, Boca Raton
Uzun B, Arslan C, Furat S (2008) Variation in fatty acid compositions, oil content and oil yield in germplasm collection of sesame (Sesamum indicum L.) J Am Oil Chem Soc 85:1135–1142
Mondal N, Bhat KV, Srivastava PS (2010) Variation in fatty acid composition in Indian germplasm of sesame. J Am Oil Chem Soc 87(11):1263–1269
Bhunia RK, Chakraborty A, Kaur R et al (2015) Analysis of fatty acid and lignan composition of Indian germplasm of sesame in terms of their nutritional merits. J Am Oil Chem Soc 92: 65–76
Aluko R (2012) Bioactive peptides. In: Functional foods and nutraceuticals, Food science text series. Springer, New York, pp 37–61
Dench JE, Rivas N, Caygill JC (1981) Selected functional properties of sesame (Sesamum indicum L.). Flour and two protein isolates. J Sci Food Agric 32:557–564. https://doi.org/10.1002/jsfa.2740320606
Frokjaer S (1994) Use of hydrolysates for protein supplementation. Food Technol 48:86–88
Giese J (1994) Proteins as ingredients: types, functions, applications. Food Technol 48:50–60
Sánchez A, Vázquez A (2017) Bioactive peptides: a review. Food Qual Saf 1(1):29–46. https://doi.org/10.1093/fqs/fyx006
Bandyopadhyay K, Ghosh S (2002) Preparation and characterization of papain-modified sesame (Sesamum indicum L.) protein isolates. J Agric Food Chem 50(23):6854–6857
Saha S, Walia S, Kundu A, Pathak N (2013) Effect of mobile phase on resolution of the isomers and homologues of tocopherols on a triacontyl stationary phase. Anal Bioanal Chem 405:9285–9295. https://doi.org/10.1007/s00216-013-7336-9
Pathak N, Rai AK, Saha S, Walia SK, Sen SK, Bhat KV (2014) Quantitative dissection of antioxidative bioactive components in cultivated and wild sesame germplasm reveals potentially exploitable wide genetic variability. J Crop Sci Biotechnol 17(3):127–139
Ashri A, Downey RK, Robbelen G (1989) Brassica species. In: Ashri A, Robbelen G, Downey RK (eds) Oil crops of the world. McGraw-Hill, New York, pp 339–382
Pathak N, Rai AK, Kumari R, Thapa A, Bhat KV (2014) Sesame crop: an underexploited oilseed holds tremendous potential for enhanced food value. Agric Sci 5(6):519–529. https://doi.org/10.4236/as.2014.56054
Wang L, Yu S, Tong C, Zhao Y, Liu Y, Song C, Zhang Y, Zhang X, Wang Y, Hua W, Li D, Li D, Li F, Yu J, Xu C, Han X, Huang S, Tai S, Wang J, Xu X, Li Y, Liu S, Varshney RK, Wang J, Zhang X (2014) Genome sequencing of the high oil crop sesame provides insight into oil biosynthesis. Genome Biol 15:R39. https://doi.org/10.1186/gb-2014-15-2-r39
Wei X, Zhu X, Yu J, Wang L, Zhang Y, Li D, Zhou R, Zhang X (2016) Identification of sesame genomic variations from genome comparison of landrace and variety. Front Plant Sci 7:1169. https://doi.org/10.3389/fpls.2016.01169
Wei X et al (2015) Genetic discovery for oil production and quality in sesame. Nat Commun 6:8609. https://doi.org/10.1038/ncomms9609
Memelink J (2004) Tailoring the plant metabolome without a loose stitch. Trends Plant Sci 7:305–307. https://doi.org/10.1016/j.tplants.2005.05.006
Hall C, Tulbek MC, Xu Y (2006) Flaxseed. Adv Food Nutr Res 51:1–97
Suh MC, Kim MJ, Hur CG, Bae JM, Park YI, Chung CH, Kang CW, Ohlrogge JB (2003) Comparative analysis of expressed sequence tags from Sesamum indicum and Arabidopsis thaliana developing seeds. Plant Mol Biol 52(6):1107–1123
Hata N, Hayashi Y, Okazawa A, Ono E, Satake H, Kobayashi A (2010) Comparison of sesamin contents and CYP81Q1 gene expressions in aboveground vegetative organs between two Japanese sesame (Sesamum indicum L.) varieties differing in seed sesamin contents. Plant Sci 178(6):510–516
Pathak N, Bhaduri A, Bhat KV, Rai AK (2015) Tracking sesamin synthase gene expression through seed maturity in wild and cultivated sesame species – a domestication footprint. Plant Biol 17(5):1039–1046. https://doi.org/10.1111/plb.12327
Acknowledgments
Ashwani K Rai gratefully acknowledges the National Academy of Sciences, India, for awarding NASI-Senior Scientist Platinum Jubilee Fellowship. Niti Pathak wishes to thank Dr. K V Bhat, NBPGR for the work carried out in his lab.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this entry
Cite this entry
Pathak, N., Bhaduri, A., Rai, A.K. (2019). Sesame: Bioactive Compounds and Health Benefits. In: Mérillon, JM., Ramawat, K.G. (eds) Bioactive Molecules in Food. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-319-78030-6_59
Download citation
DOI: https://doi.org/10.1007/978-3-319-78030-6_59
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-78029-0
Online ISBN: 978-3-319-78030-6
eBook Packages: Chemistry and Materials ScienceReference Module Physical and Materials ScienceReference Module Chemistry, Materials and Physics