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Antihypertensive Peptides from Animal Proteins

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Book cover Bioactive Molecules in Food

Part of the book series: Reference Series in Phytochemistry ((RSP))

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Abstract

Hypertension is considered a major health problem throughout the world among adults, adolescents, as well as children and several preventive and therapeutic interventions are available. In addition to the pharmaceutical drugs and lifestyle changes, significant milestones have been achieved in the past decades in the identification of bioactive peptides from animal proteins with useful antihypertensive activities. The antihypertensive properties of these peptides are attributed to several mechanisms ranging from mineral-binding, opioid-like and antithrombotic properties to inhibition of ACE (angiotensin-converting enzyme). ACE-inhibitory peptides are the most widely studied bioactive peptides with promising potential in hypertension management. In addition to milk and dairy products, which are the major sources of antihypertensive peptides, a remarkable increase has been observed in the documentation of peptides from other animal proteins, such as meat, with demonstrated in vitro and in vivo antihypertensive properties. Numerous opportunities exist in the global market for the development of novel food products and additives based on these antihypertensive peptides for the dietary management of hypertension. This chapter reviews the antihypertensive peptides derived from meat proteins and examines their possible role as a functional ingredient in foods for the management of hypertension.

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Authors and Affiliations

  1. Division of Livestock Products Technology, Faculty of Veterinary Sciences and Animal Husbandry, Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu, Jammu, Jammu and Kashmir, India

    Z. F. Bhat

  2. Department of Wine Food and Molecular Biosciences, Faculty of Agriculture and Life Sciences, Lincoln University, Christchurch, New Zealand

    Susan Mason & James D. Morton

  3. Department of Food Sciences, University of Otago, Dunedin, New Zealand

    Alaa El-Din A. Bekhit

  4. Division of Biotechnology, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Alusteng, Srinagar, Jammu and Kashmir, India

    Hina F. Bhat

Authors
  1. Z. F. Bhat
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  2. Susan Mason
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  3. James D. Morton
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  4. Alaa El-Din A. Bekhit
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  5. Hina F. Bhat
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Corresponding author

Correspondence to Z. F. Bhat .

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Editors and Affiliations

  1. Faculty of Pharmaceutical Sciences, Institute of Vine and Wine Sciences, University of Bordeaux, Villenave d’Ornon, France

    Jean-Michel Mérillon

  2. Department of Botany, University College of Science, M. L. Sukhadia University, Udaipur, Rajasthan, India

    Kishan Gopal Ramawat

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Bhat, Z.F., Mason, S., Morton, J.D., Bekhit, A.ED.A., Bhat, H.F. (2019). Antihypertensive Peptides from Animal Proteins. In: Mérillon, JM., Ramawat, K.G. (eds) Bioactive Molecules in Food. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-319-78030-6_18

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