Abstract
A range of retroperitoneal, metastatic, and pelvic malignancies cause urinary tract obstruction via direct spread or extrinsic compression of the urinary tract, particularly the ureters. Urinary tract obstruction, secondary to malignancy, poses a myriad of challenges to the health practitioner due to significant morbidities arising from acute kidney injury and end-stage renal disease. There is a crucial need to alleviate acute symptoms and preserve renal function via catheterization, stents, or surgery while addressing the primary disease. This chapter provides an available up to date data on this oncologic emergency and its management.
References
Arthur RR, Shah KV, Baust SJ, et al. Association of BK viruria with hemorrhagic cystitis in recipients of bone marrow transplants. N Engl J Med. 1986;315(4): 230–4.
Batlle DC, Arruda JA, Kurtzman NA. Hyperkalemic distal renal tubular acidosis associated with obstructive uropathy. N Engl J Med. 1981;304(7):373–80.
Bedi A, Miller CB, Hanson JL, et al. Association of BK virus with failure of prophylaxis against hemorrhagic cystitis following bone marrow transplantation. J Clin Oncol. 1995;13(5):1103–9.
Brien JC, Shariat SF, Herman MP, et al. Preoperative hydronephrosis, ureteroscopic biopsy grade and urinary cytology can improve prediction of advanced upper tract urothelial carcinoma. J Urol. 2010;184(1): 69–73.
Cho KS, Hong SJ, Cho NH, et al. Grade of hydronephrosis and tumor diameter as preoperative prognostic factors in ureteral transitional cell carcinoma. Urology. 2007;70(4):662–6.
Geddes CC, Gunson R, Mazonakis E, et al. BK viremia surveillance after kidney transplant: single-center experience during a change from cyclosporine-to lower-dose tacrolimus-based primary immunosuppression regimen. Transplant Infect Dis. 2011;13(2): 109–16.
Harkensee C, Vasdev N, Gennery AR, et al. Prevention and management of BK-virus associated haemorrhagic cystitis in children following haematopoietic stem cell transplantation–a systematic review and evidence-based guidance for clinical management. Br J Haematol. 2008;142(5):717–31.
Hwang SJ, Haas M, Harris HW Jr, et al. Transport defects of rabbit medullary thick ascending limb cells in obstructive nephropathy. J Clin Invest. 1993;91(1): 21–8.
Ito Y, Kikuchi E, Tanaka N, et al. Preoperative hydronephrosis grade independently predicts worse pathological outcomes in patients undergoing nephroureterectomy for upper tract urothelial carcinoma. J Urol. 2011;185(5):1621–6.
Khan H, Oberoi S, Mahvash A, et al. Reversible ureteral obstruction due to polyomavirus infection after percutaneous nephrostomy catheter placement. Biol Blood Marrow Transplant. 2011;17(10):1551–5.
Klahr S. New insights into the consequences and mechanisms of renal impairment in obstructive nephropathy. Am J Kidney Dis. 1991;18(6):689–99.
Kocurek JN, Orihuela E, Saltzstein DR. Nondilated obstructive uropathy and renal failure as a result of carcinoma of the intrapelvic area. Surg Gynecol Obstet. 1991;173(6):470–2.
Kouba E, Wallen EM, Pruthi RS. Management of ureteral obstruction due to advanced malignancy: optimizing therapeutic and palliative outcomes. J Urol. 2008;180(2):444–50.
Madsen MG, Nørregaard R, Frøkiær J, et al. Urinary biomarkers in prenatally diagnosed unilateral hydronephrosis. J Pediatr Urol. 2011;7(2):105–12.
Mcinnes EG, Levy DW, Chaudhuri MD, et al. Renal failure in the elderly. Q J Med. 1987;64(243):583.
Ng CK, Shariat SF, Lucas SM, et al. Does the presence of hydronephrosis on preoperative axial CT imaging predict worse outcomes for patients undergoing nephroureterectomy for upper-tract urothelial carcinoma. Urol Oncol. 2011;29(1):27–32.
Pahari A, Rees L. BK virus-associated renal problems–clinical implications. Pediatr Nephrol (Berlin, Germany). 2003;18(8):743–8.
Pradhan TS, Duan H, Katsoulakis E, et al. Hydronephrosis as a prognostic indicator of survival in advanced cervix cancer. Int J Gynecol Cancer. 2011;21(6):1091–6.
Rademakers K, Drake MJ, Gammie A, et al. Male bladder outlet obstruction: time to re-evaluate the definition and reconsider our diagnostic pathway? ICI-RS 2015. Neurourol Urodyn. 2017;36(4):894–901.
Savva-Bordalo J, Pinho Vaz C, Sousa M, et al. Clinical effectiveness of hyperbaric oxygen therapy for BK-virus-associated hemorrhagic cystitis after allogeneic bone marrow transplantation. Bone Marrow Transplant. 2012;47(8):1095–8.
Schreiner GF, Kohan DE. Regulation of renal transport processes and hemodynamics by macrophages and lymphocytes. Am J Phys. 1990;258(4 Pt 2):F761–7.
Soper JT, Blaszczyk TM, Oke E, et al. Percutaneous nephrostomy in gynecologic oncology patients. Am J Obstet Gynecol. 1988;158(5):1126–31.
Spital A, Spataro R. Nondilated obstructive uropathy due to a ureteral calculus. Am J Med. 1995;98(5): 509–11.
Tanner GA, Knopp LC. Glomerular blood flow after single nephron obstruction in the rat kidney. Am J Phys. 1986;250(1 Pt 2):F77–85.
Tseng TY, Stoller ML. Obstructive uropathy. Clin Geriatr Med. 2009;25(3):437–43.
Vaglio A, Salvarani C, Buzio C. Retroperitoneal fibrosis. Lancet. 2006;367(9506):241–51.
Webb JA. Ultrasonography in the diagnosis of renal obstruction. BMJ. 1990;301(6758):944–6.
Wong LM, Cleeve LK, Milner AD, et al. Malignant ureteral obstruction: outcomes after intervention. Have things changed? J Urol. 2007;178(1): 178–83;Discussion 183
Zeisberg M, Neilson EG. Mechanisms of tubulointerstitial fibrosis. J Am Soc Nephrol. 2010;21(11): 1819–34.
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Kalu, C.O., Abudyayeh, A. (2019). Obstructive Uropathy in Critically Ill Cancer Patients. In: Nates, J., Price, K. (eds) Oncologic Critical Care. Springer, Cham. https://doi.org/10.1007/978-3-319-74698-2_78-1
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