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Contemporary Oral Medicine pp 2135–2185Cite as

Orofacial Pain in the Medically Complex Patient

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Abstract

Orofacial pain may be the presenting feature of a number of systemic and medical disorders, and clinicians should be aware of the possibility of these rare causes of pain in the orofacial region. Cardiovascular, cerebrovascular, musculoskeletal, hematological, inflammatory, neurological, malignant, and iatrogenic causes for orofacial pain presentations are discussed in this chapter. “Red flags” and significant clinical features of these conditions are presented. The importance of considering medical or systemic causes in the differential diagnosis of orofacial pain is discussed.

With acknowledgements to Professor Joanna M. Zakrzewska and Dr Eric Lessard.

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References

  • Aaron LA, Burke MM, Buchwald D. Overlapping conditions among patients with chronic fatigue syndrome, fibromyalgia, and temporomandibular disorder. Arch Intern Med. 2000;160(2):221–7.

    PubMed  Google Scholar 

  • Afari N, Ahumada SM, Wright LJ, Mostoufi S, Golnari G, Reis V, et al. Psychological trauma and functional somatic syndromes. Psychosom Med. 2014;76(1):2–11.

    Article  PubMed  Google Scholar 

  • Aghaloo TL, Tetradis S. Osteonecrosis of the jaw in the absence of antiresorptive or antiangiogenic exposure: a series of 6 cases. J Oral Maxillofac Surg. 2017;75(1):129–42.

    Article  PubMed  Google Scholar 

  • Agius AM, Sama A. Rhinogenic and nonrhinogenic headaches. Curr Opin Otolaryngol Head Neck Surg. 2015;23(1):15–20.

    Article  PubMed  Google Scholar 

  • Agius AM, Jones NS, Muscat R. Is “sinus” pain really sinusitis? Br J Hosp Med (Lond). 2014;75(10):558–63.

    Article  Google Scholar 

  • Ah-See KL, MacKenzie J, practitioner G, Ah-See KW. Management of chronic rhinosinusitis. BMJ. 2012;345(1):e7054.

    Article  PubMed  Google Scholar 

  • Albanese A, Romito LM, Calandrella D. Therapeutic advances in dystonia. Mov Disord. 2015;30(11):1547–56. Goetz CG, Poewe W, editors.

    Article  PubMed  Google Scholar 

  • Ali R, Oxlade C, Borkowska E. Sickle cell toothache. Br Dent J. 2008;205(10):524.

    Article  PubMed  Google Scholar 

  • Alon EE, Ekbom DC. Neurosarcoidosis affecting the vagus nerve. Ann Otol Rhinol Laryngol. 2010;119(9):641–5.

    Article  PubMed  Google Scholar 

  • Amaral TN, Peres FA, Lapa AT, Marques-Neto JF, Appenzeller S. Neurologic involvement in scleroderma: a systematic review. Semin Arthritis Rheum. 2013;43(3):335–47. Elsevier.

    Article  PubMed  Google Scholar 

  • American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Arlington: American Psychiatric Publishing; 2013.

    Book  Google Scholar 

  • Amin A, Balderacchi JL. Trigeminal neurosarcoidosis: case report and literature review. Ear Nose Throat J. 2010;89(7):320–2.

    PubMed  Google Scholar 

  • Anand P, Bley K. Topical capsaicin for pain management: therapeutic potential and mechanisms of action of the new high-concentration capsaicin 8% patch. Br J Anaesth. 2011;107(4):490–502.

    Article  PubMed  PubMed Central  Google Scholar 

  • Aquino CCH, Lang AE. Tardive dyskinesia syndromes: current concepts. Parkinsonism Relat Disord. 2013;20(S1):S113–7. Elsevier.

    Google Scholar 

  • Arap A, Siqueira SRDT, Silva CB, Teixeira MJ, Siqueira JTT. Trigeminal pain and quantitative sensory testing in painful peripheral diabetic neuropathy. Arch Oral Biol. 2010;55(7):486–93. Elsevier Ltd.

    Article  PubMed  Google Scholar 

  • Ashworth B, Tait GB. Trigeminal neuropathy in connective tissue disease. Neurology. 1971;21(6):609–14.

    Article  PubMed  Google Scholar 

  • Bakke M, Larsen BM, Dalager T, Møller E. Oromandibular dystonia – functional and clinical characteristics: a report on 21 cases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115(1):e21–6.

    Article  PubMed  Google Scholar 

  • Balasubramaniam R, de Leeuw R, Zhu H, Nickerson RB, Okeson JP, Carlson CR. Prevalence of temporomandibular disorders in fibromyalgia and failed back syndrome patients: a blinded prospective comparison study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;104(2):204–16.

    Article  PubMed  Google Scholar 

  • Balasubramaniam R, Rasmussen J, Carlson LW, Van Sickels JE, Okeson JP. Oromandibular dystonia revisited: a review and a unique case. J Oral Maxillofac Surg. 2008;66(2):379–86.

    Article  PubMed  Google Scholar 

  • Baron R, Allegri M, Correa-Illanes G, Hans G, Serpell M, Mick G, et al. The 5% lidocaine-medicated plaster: its inclusion in international treatment guidelines for treating localized neuropathic pain, and clinical evidence supporting its use. Pain Ther. 2016;5(2):149–69. Springer Healthcare.

    Article  PubMed  PubMed Central  Google Scholar 

  • Barsky AJ, Borus JF. Functional somatic syndromes. Ann Intern Med. 1999;130(11):910–21.

    Article  PubMed  Google Scholar 

  • Basati MS. Sickle cell disease and pulpal necrosis: a review of the literature for the primary care dentist. Prim Dent J. 2014;3(1):76–9.

    Article  PubMed  Google Scholar 

  • Baykul T, Aydin MA, Nasir S. Avascular necrosis of the mandibular condyle causing fibrous ankylosis of the temporomandibular joint in sickle cell anemia. J Craniofac Surg. 2004;15(6):1052–6.

    Article  PubMed  Google Scholar 

  • Beddis HP, Davies SJ, Budenberg A, Horner K, Pemberton MN. Temporomandibular disorders, trismus and malignancy: development of a checklist to improve patient safety. Br Dent J. 2014;217(7):351–5. Nature Publishing Group.

    Article  PubMed  Google Scholar 

  • Benoliel R, Biron A, Quek SYP, Nahlieli O, Eliav E. Trigeminal neurosensory changes following acute and chronic paranasal sinusitis. Quintessence Int. 2006;37(6):437–43.

    PubMed  Google Scholar 

  • Benoliel R, Eliav E, Sharav Y. Classification of chronic orofacial pain: applicability of chronic headache criteria. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110(6):729–37.

    Article  PubMed  Google Scholar 

  • Berk C, Constantoyannis C, Honey CR. The treatment of trigeminal neuralgia in patients with multiple sclerosis using percutaneous radiofrequency rhizotomy. Can J Neurol Sci. 2003;30(3):220–3.

    Article  PubMed  Google Scholar 

  • Bhidayasiri R, Cardoso F, Truong DD. Botulinum toxin in blepharospasm and oromandibular dystonia: comparing different botulinum toxin preparations. Eur J Neurol. 2006;13(Suppl 1):21–9.

    Article  PubMed  Google Scholar 

  • Bhidayasiri R, Fahn S, Weiner WJ, Gronseth GS, Sullivan KL, Zesiewicz TA, et al. Evidence-based guideline: treatment of tardive syndromes: report of the Guideline Development Subcommittee of the American Academy of Neurology. Neurology. 2013;81(5):463–9.

    Article  PubMed  Google Scholar 

  • Bigal ME, Lipton RB. The differential diagnosis of chronic daily headaches: an algorithm-based approach. J Headache Pain. 2007;8(5):263–72.

    Article  PubMed  PubMed Central  Google Scholar 

  • Bindoff LA, Heseltine D. Unilateral facial pain in patients with lung cancer: a referred pain via the vagus? Lancet. 1988;1(8589):812–5.

    Article  PubMed  Google Scholar 

  • Biousse V, D’Anglejan-Chatillon J, Massiou H, Bousser MG. Head pain in non-traumatic carotid artery dissection: a series of 65 patients. Cephalalgia. 1994;14(1):33–6.

    Article  PubMed  Google Scholar 

  • Blanchet PJ, Rompre PH, Lavigne GJ, Lamarche C. Oral dyskinesia: a clinical overview. Int J Prosthodont. 2005;18(1):10–9.

    PubMed  Google Scholar 

  • Bonica JJ. The need of a taxonomy. Pain. 1979;6(3):247–8.

    Article  Google Scholar 

  • Bookland MJ, Bagley CA, Schwarz J, Burger PC, Brem H. Intracavernous trigeminal ganglion amyloidoma: case report. Neurosurgery. 2007;60(3):E574; discussion E574.

    Article  PubMed  Google Scholar 

  • Bowsher D. The effects of pre-emptive treatment of postherpetic neuralgia with amitriptyline: a randomized, double-blind, placebo-controlled trial. J Pain Symptom Manage. 1997;13(6):327–31.

    Article  PubMed  Google Scholar 

  • Boysen G, Galassi G, Kamieniecka Z. Familial amyloidosis with cranial neuropathy and corneal lattice dystrophy. J Neurol. 1979;42:1020–1030.

    Article  Google Scholar 

  • Braksick S, Shah-Haque S, El-Haddad B, Moussa R. Neurosarcoidosis presenting as trigeminal nevralgia: a case report and review of the literature. Sarcoidosis Vasc Diffuse Lung Dis. 2013;30(2):153–6.

    PubMed  Google Scholar 

  • Budtz-Lilly A, Schröder A, Rask MT, Fink P, Vestergaard M, Rosendal M. Bodily distress syndrome: a new diagnosis for functional disorders in primary care? BMC Fam Pract. 2015;16:1–10.

    Google Scholar 

  • Caracas MDS, Jales SP, Jales Neto LH, da Silva Castro JC, Suganuma LM, Fonseca GHH, et al. Temporomandibular joint arthritis in sickle cell disease: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115(2):e31–5.

    Article  Google Scholar 

  • Carlson ML, White JR, Espahbodi M, Haynes DS, Driscoll CLW, Aksamit AJ, et al. Cranial base manifestations of neurosarcoidosis: a review of 305 patients. Otol Neurotol. 2015;36(1):156–66.

    PubMed  Google Scholar 

  • Casamassimo PS, Tucker-Lammertse JE. Diabetic polyradiculopathy with trigeminal nerve involvement. A case report. Oral Surg Oral Med Oral Pathol. 1988;66(3):315–7.

    Article  PubMed  Google Scholar 

  • Cashman EC, Smyth D. Primary headache syndromes and sinus headache: An approach to diagnosis and management. Auris Nasus Larynx. 2012;39(3):257–60. Elsevier Ireland Ltd.

    Article  PubMed  Google Scholar 

  • Chapman MN, Fujita A, Sung EK, Siegel C, Nadgir RN, Saito N, et al. Sarcoidosis in the head and neck: an illustrative review of clinical presentations and imaging findings. Am J Roentgenol. 2017;208(1):66–75.

    Article  Google Scholar 

  • Chen N, Yang M, He L, Zhang D, Zhou M, Zhu C. Corticosteroids for preventing postherpetic neuralgia. Cochrane Database Syst Rev. 2010;(12):CD005582.

    Google Scholar 

  • Chen N, Li Q, Yang J, Zhou M, Zhou D, He L. Antiviral treatment for preventing postherpetic neuralgia. Cochrane Database Syst Rev. 2014;(2):CD006866.

    Google Scholar 

  • Cheng W-C, Chang C-N. Trigeminal neuralgia caused by contralateral supratentorial meningioma. J Clin Neurosci. 2008;15(10):1162–3.

    Article  PubMed  Google Scholar 

  • Churchill CH, Abril A, Krishna M, Callman ML, Ginsburg WW. Jaw claudication in primary amyloidosis: unusual presentation of a rare disease. J Rheumatol. 2003;30(10):2283–6.

    PubMed  Google Scholar 

  • Clark GT. The management of oromandibular motor disorders and facial spasms with injections of botulinum toxin. Phys Med Rehabil Clin N Am. 2003;14(4):727–48.

    Article  PubMed  Google Scholar 

  • Clark GT, Ram S. Four oral motor disorders: bruxism, dystonia, dyskinesia and drug-induced dystonic extrapyramidal reactions. Dent Clin North Am. 2007;51(1):225–43.

    Article  PubMed  Google Scholar 

  • Clauw DJ. Fibromyalgia: a clinical review. JAMA. 2014;311(15):1547–1555.

    Article  PubMed  Google Scholar 

  • Clifton NJ, Jones NS. Prevalence of facial pain in 108 consecutive patients with paranasal mucopurulent discharge at endoscopy. J Laryngol Otol. 2007;121(4):345–8.

    Article  PubMed  Google Scholar 

  • Colloca L, Ludman T, Bouhassira D, Baron R, Dickenson AH, Yarnitsky D, et al. Neuropathic pain. Nat Rev Dis Primers. 2017;3:1–20. Nature Publishing Group. Macmillan Publishers Limited.

    Google Scholar 

  • Colosimo C, Suppa A, Fabbrini G, Bologna M, Berardelli A. Craniocervical dystonia: clinical and pathophysiological features. Eur J Neurol. 2010;17:15–21.

    Article  PubMed  Google Scholar 

  • Costa CPS, Thomaz EBAF, Souza S de FC. Association between sickle cell anemia and pulp necrosis. J Endod. 2013;39(2):177–81.

    Article  PubMed  Google Scholar 

  • Cox GM. A study of oral pain experience in sickle cell patients. Oral Surg Oral Med Oral Pathol. 1984;58(1):39–41.

    Article  PubMed  Google Scholar 

  • Creed F, Henningsen P, Fink P, editors. Medically unexplained symptoms, somatisation and bodily distress. Developing better clinical services. Cambridge: Cambridge University Press; 2011.

    Google Scholar 

  • Croft A, Thompson N, Duddy M, Khattak F, Mollan S, Jobanputra P. OP0056 Can we replace temporal artery biopsy with cranial ultrasound for the diagnosis of GIANT cell arteritis? A retrospective cohort study of the diagnostic utility of ultrasound in routine clinical practice. Ann Rheum Dis. 2014;73(Suppl 2):82.

    Article  Google Scholar 

  • Danesh-Sani SA, Rahimdoost A, Soltani M, Ghiyasi M, Haghdoost N, Sabzali-Zanjankhah S. Clinical assessment of orofacial manifestations in 500 patients with multiple sclerosis. J Oral Maxillofac Surg. 2013;71(2):290–4.

    Article  PubMed  Google Scholar 

  • Dasgupta B, Borg FA, Hassan N, Alexander L, Barraclough K, Bourke B, et al. BSR and BHPR guidelines for the management of giant cell arteritis. Rheumatology. 2010;49(8):1594–7.

    Article  PubMed  Google Scholar 

  • Debette S, Leys D. Cervical-artery dissections: predisposing factors, diagnosis, and outcome. Lancet Neurol. 2009;8(7):668–78. Elsevier Ltd.

    Article  PubMed  Google Scholar 

  • Dodick DW. Clinical practice. Chronic daily headache. N Engl J Med. 2006;354(2):158–65.

    Article  PubMed  Google Scholar 

  • Doi H, Nakamura M, Suenaga T, Hashimoto S. Transient eye and nose pain as an initial symptom of pontine infarction. Neurology. 2003;60(3):521–3.

    Article  PubMed  Google Scholar 

  • Dressler D. Botulinum toxin for treatment of dystonia. Eur J Neurol. 2010;17(Suppl 2):88–96.

    Article  PubMed  Google Scholar 

  • Dworkin RH, Johnson RW, Breuer J, Gnann JW, Levin MJ, Backonja M, et al. Recommendations for the management of herpes zoster. Clin Infect Dis. 2007;44(Suppl 1):S1–26.

    Article  PubMed  Google Scholar 

  • Dworkin RH, Gnann JWJ, Oaklander AL, Raja SN, Schmader KE, Whitley RJ. Diagnosis and assessment of pain associated with herpes zoster and postherpetic neuralgia. J Pain. 2008;9(1 Suppl 1):S37–44.

    Article  PubMed  Google Scholar 

  • Epidemiology|International Osteoporosis Foundation [Internet]. iofbonehealth.org. [cited 15 June 2016]. Available from https://www.iofbonehealth.org/epidemiology.

  • Eweiss AZ, Lund VJ, Barlow J, Rose G. Do patients with chronic rhinosinusitis with nasal polyps suffer with facial pain? Rhinology. 2013;51(3):231–5.

    Article  PubMed  Google Scholar 

  • Fahy C, Jones NS. Nasal polyposis and facial pain. Clin Otolaryngol Allied Sci. 2001;26(6):510–3.

    Article  PubMed  Google Scholar 

  • Fedele S, Porter SR, D’Aiuto F, Aljohani S, Vescovi P, Manfredi M, et al. Nonexposed variant of bisphosphonate-associated osteonecrosis of the jaw: a case series. Am J Med. 2010;123(11):1060–4.

    Article  PubMed  Google Scholar 

  • Feldkamp J, Becker A, Witte OW, Scharff D, Scherbaum WA. Long-term anticonvulsant therapy leads to low bone mineral density – evidence for direct drug effects of phenytoin and carbamazepine on human osteoblast-like cells. Exp Clin Endocrinol Diabetes. 2000;108(1):37–43.

    PubMed  Google Scholar 

  • Fink P, Schröder A. One single diagnosis, bodily distress syndrome, succeeded to capture 10 diagnostic categories of functional somatic syndromes and somatoform disorders. J Psychosom Res. 2010;68(5):415–26. Elsevier Inc.

    Article  PubMed  Google Scholar 

  • Fisher CM. The headache and pain of spontaneous carotid dissection. Headache. 1982;22(2):60–5.

    Article  PubMed  Google Scholar 

  • Fitzpatrick LA. Pathophysiology of bone loss in patients receiving anticonvulsant therapy. Epilepsy Behav. 2004;5(Suppl 2):S3–15.

    Article  PubMed  Google Scholar 

  • Foley PL, Vesterinen HM, Laird BJ, Sena ES, Colvin LA, Chandran S, et al. Prevalence and natural history of pain in adults with multiple sclerosis: systematic review and meta-analysis. Pain. 2013;154(5):632–42. International Association for the Study of Pain.

    Article  PubMed  Google Scholar 

  • Font J, Ramos-Casals M, de la Red G, Pou A, Casanova A, García-Carrasco M, et al. Pure sensory neuropathy in primary Sjögren’s syndrome. Longterm prospective followup and review of the literature. J Rheumatol. 2003;30(7):1552–7.

    PubMed  Google Scholar 

  • Fowler TJ, Scadding JW, Losseff N, Scadding JW. Clinical neurology. 4th ed. London: Taylor & Francis; 2011.

    Google Scholar 

  • Frances A. The new somatic symptom disorder in DSM-5 risks mislabeling many people as mentally ill. BMJ. 2013;346:f1580.

    Article  PubMed  Google Scholar 

  • Fricton JR. The relationship of temporomandibular disorders and fibromyalgia: implications for diagnosis and treatment. Curr Pain Headache Rep. 2004;8(5):355–63.

    Article  PubMed  Google Scholar 

  • Fricton JR, Kroening R, Haley D, Siegert R. Myofascial pain syndrome of the head and neck: a review of clinical characteristics of 164 patients. Oral Surg Oral Med Oral Pathol. 1985;60(6):615–23.

    Article  PubMed  Google Scholar 

  • Gagliardi AM, Andriolo BN, Torloni MR, Soares BG. Vaccines for preventing herpes zoster in older adults, vol. 178. Chichester, UK: Wiley; 1996. 1p.

    Google Scholar 

  • Galán Gil S, Peñarrocha Diago M, Peñarrocha Diago M. Malignant mental nerve neuropathy: systematic review. Med Oral Patol Oral Cir Bucal. 2008;13(10):E616–21.

    PubMed  Google Scholar 

  • Gallotta S, Bruno V, Catapano S, Mobilio N, Ciacci C, Iovino P. High risk of temporomandibular disorder in irritable bowel syndrome: is there a correlation with greater illness severity? World J Gastroenterol. 2017;23(1):103–9.

    Article  PubMed  PubMed Central  Google Scholar 

  • Gandhi D, Gujar S, Mukherji SK. Magnetic resonance imaging of perineural spread of head and neck malignancies. Top Magn Reson Imaging. 2004;15(2):79–85.

    Article  PubMed  Google Scholar 

  • Genereau T, Lortholary O, Pottier MA, Michon-Pasturel U, Ponge T, de Wazières B, et al. Temporal artery biopsy: a diagnostic tool for systemic necrotizing vasculitis. French Vasculitis Study Group. Arthritis Rheum. 1999;42(12):2674–81.

    Article  PubMed  Google Scholar 

  • Germano G, Monti S, Ponte C, Possemato N, Caporali R, Salvarani C, et al. The role of ultrasound in the diagnosis and follow-up of large-vessel vasculitis: an update. Clin Exp Rheumatol. 2017;35 Suppl 103(1):194–8.

    PubMed  Google Scholar 

  • Gertz MA, Kyle RA, Griffing WL, Hunder GG. Jaw claudication in primary systemic amyloidosis. Medicine. 1986;65(3):173–9.

    Article  PubMed  Google Scholar 

  • Gleeson M, editor. Scott-Brown’s otorhinolaryngology: head and neck surgery. 7th ed, 3 volume set. London: CRC Press; 2008.

    Google Scholar 

  • Goadsby PJ. Pathophysiology of cluster headache: a trigeminal autonomic cephalgia. Lancet Neurol. 2002;1(4):251–7.

    Article  PubMed  Google Scholar 

  • Gottfried O, Chin S, Davidson H, Couldwell W. Trigeminal amyloidoma: case report and review of the literature. Skull Base. 2007;17(5):317–24.

    Article  PubMed  PubMed Central  Google Scholar 

  • Grant IA, Hunder GG, Homburger HA, Dyck PJ. Peripheral neuropathy associated with sicca complex. Neurology. 1997;48(4):855–62.

    Article  PubMed  Google Scholar 

  • Grant SWJ, Underhill HC, Atkin P. Giant cell arteritis affecting the tongue: a case report and review of the literature. Dent Update. 2013;40(8):669–70, 673–4, 677.

    Article  PubMed  Google Scholar 

  • Gureje O, Reed GM. Bodily distress disorder in ICD-11: problems and prospects. World Psychiatry. 2016;15(3):291–2.

    Article  PubMed  PubMed Central  Google Scholar 

  • Hadley GR, Gayle JA, Ripoll J, Jones MR, Argoff CE, Kaye RJ, et al. Post-herpetic neuralgia: a review. Curr Pain Headache Rep. 2016;20(3):21.

    Article  Google Scholar 

  • Hagen NA, Stevens JC, Michet CJ. Trigeminal sensory neuropathy associated with connective tissue diseases. Neurology. 1990;40(6):891–6.

    Article  PubMed  Google Scholar 

  • Hallett M, Albanese A, Dressler D, Segal KR, Simpson DM, Truong D, et al. Evidence-based review and assessment of botulinum neurotoxin for the treatment of movement disorders. Toxicon. 2013;67(C):94–114. Elsevier Ltd.

    Article  PubMed  Google Scholar 

  • Hant FN, Bolster MB. Drugs that may harm bone: mitigating the risk. Cleve Clin J Med. 2016;83(4):281–8.

    Article  PubMed  Google Scholar 

  • Harper DE, Schrepf A, Clauw DJ. Pain mechanisms and centralized pain in temporomandibular disorders. J Dent Res. 2016;95(10):1102–8.

    Article  PubMed  PubMed Central  Google Scholar 

  • Harrison L, Jones NS. Intranasal contact points as a cause of facial pain or headache: a systematic review. Clin Otolaryngol. 2013;38(1):8–22.

    Article  PubMed  Google Scholar 

  • Häuser W, Ablin J, Fitzcharles M-A, Littlejohn G, Luciano JV, Usui C, et al. Fibromyalgia. Nat Rev Dis Primers. 2015;78:15022. Nature Publishing Group.

    Google Scholar 

  • Heir GM. Differentiation of orofacial pain related to Lyme disease from other dental and facial pain disorders. Dent Clin North Am. 1997;41(2):243–58.

    PubMed  Google Scholar 

  • Heir G. Post herpetic trigeminal neuropathy. In: Ernberg M, Alstergren P, editors. Clinical cases in orofacial pain. Hoboken, NJ: Wiley-Blackwell. 2017; 7p.

    Google Scholar 

  • Heir GM, Fein LA. Lyme disease: considerations for dentistry. J Orofac Pain. 1996;10(1):74–86.

    PubMed  Google Scholar 

  • Helliwell TR. Non-infectious inflammatory lesions of the sinonasal tract. Head Neck Pathol. 2016;10(1):32–9. Springer US.

    Google Scholar 

  • Hevner R, Vilela M, Rostomily R, Cohrs R. An unusual cause of trigeminal-distribution pain and tumour. Lancet. 2003;2(9):567–571.

    Article  PubMed  Google Scholar 

  • IHS – International Headache Society. Central post-stroke pain [G46.21]|13.18.2|G44.810 [Internet]. ihs-classification.org. [cited 15 June 2016]. Available from https://www.ichd-3.org/13-painful-cranial-neuropathies-and-other-facial-pains/13-12-central-neuropathic-pain/13-12-2-central-post-stroke-pain-cpsp/.

  • Imam I. Neurological manifestations of HIV infection in Nigerians. Afr J AIDS Res. 2007;6(2):187–92.

    Article  PubMed  Google Scholar 

  • Jääskeläinen SK. Pathophysiology of primary burning mouth syndrome. Clin Neurophysiol. 2012;123(1):71–7.

    Article  PubMed  Google Scholar 

  • Jääskeläinen SK, Woda A. Burning mouth syndrome. Cephalalgia. 2017;37(7):627–47.

    Article  PubMed  Google Scholar 

  • Jinnah HA, Factor SA. Diagnosis and treatment of dystonia. Neurol Clin. 2015;33(1):77–100.

    Article  PubMed  PubMed Central  Google Scholar 

  • Johnson RW, Rice ASC. Postherpetic neuralgia. N Engl J Med. 2014;371(16):1526–33. Solomon CG, editor.

    Article  PubMed  Google Scholar 

  • Jones NS. Sinogenic facial pain: diagnosis and management. Otolaryngol Clin North Am. 2005;38(6):1311–1325, x–xi.

    Article  PubMed  Google Scholar 

  • Jones NS. The prevalence of facial pain and purulent sinusitis. Curr Opin Otolaryngol Head Neck Surg. 2009;17(1):38–42.

    Article  PubMed  Google Scholar 

  • Jones RCW, Lawson E, Backonja M. Managing neuropathic pain. Med Clin North Am. 2016;100(1):151–67.

    Article  PubMed  Google Scholar 

  • Kalladka M, Proter N, Benoliel R, Czerninski R, Eliav E. Mental nerve neuropathy: patient characteristics and neurosensory changes. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(3):364–70.

    Article  PubMed  Google Scholar 

  • Karp B, Alter K. Botulinum toxin treatment of blepharospasm, orofacial/oromandibular dystonia, and hemifacial spasm. Semin Neurol. 2016;36(01):084–91.

    Article  Google Scholar 

  • Kasravi N, Leung A, Silver I, Burneo JG. Dissection of the internal carotid artery causing Horner syndrome and palsy of cranial nerve XII. CMAJ. 2010;182(9):E373–7.

    Article  PubMed  PubMed Central  Google Scholar 

  • Katz J, Rosenbloom BN, Fashler S. Chronic pain, psychopathology, and DSM-5 somatic symptom disorder. Can J Psychiatry. 2015;60(4):160–7.

    Article  PubMed  PubMed Central  Google Scholar 

  • Kawai K, Rampakakis E, Tsai T-F, Cheong HJ, Dhitavat J, Covarrubias AO, et al. Predictors of postherpetic neuralgia in patients with herpes zoster: a pooled analysis of prospective cohort studies from North and Latin America and Asia. Int J Infect Dis. 2015;34:126–31. International Society for Infectious Diseases.

    Article  PubMed  Google Scholar 

  • Khan J, Heir GM, Quek SYP. Cerebellopontine angle (CPA) tumor mimicking dental pain following facial trauma. Cranio. 2010;28(3):205–8.

    Article  PubMed  Google Scholar 

  • Khouzam HR. Identification and management of tardive dyskinesia: a case series and literature review. Postgrad Med. 2015;127(7):726–37. 2nd ed.

    Article  PubMed  Google Scholar 

  • Kim Y-K, Schulman S. Cervical artery dissection: pathology, epidemiology and management. Thromb Res. 2009;123(6):810–21. Elsevier.

    Article  PubMed  Google Scholar 

  • Koopman JSHA, Dieleman JP, Huygen FJ, de Mos M, Martin CGM, Sturkenboom MCJM. Incidence of facial pain in the general population. Pain. 2009;147(1–3):122–7.

    Article  PubMed  Google Scholar 

  • Kreiner M, Okeson JP, Michelis V, Lujambio M, Isberg A. Craniofacial pain as the sole symptom of cardiac ischemia: a prospective multicenter study. J Am Dent Assoc. 2007;138(1):74–9.

    Article  PubMed  Google Scholar 

  • Kreiner M, Falace D, Michelis V, Okeson JP, Isberg A. Quality difference in craniofacial pain of cardiac vs. dental origin. J Dent Res. 2010;89(9):965–9.

    Article  PubMed  Google Scholar 

  • Kreiner M, Alvarez R, Waldenström A, Michelis V, Muñiz R, Isberg A. Craniofacial pain of cardiac origin is associated with inferior wall ischemia. J Oral Facial Pain Headache. 2014;28(4):317–21.

    Article  PubMed  Google Scholar 

  • Kumar P, Clark M, editors. Kumar and Clark’s clinical medicine. 9th ed. London: Elsevier; 2016.

    Google Scholar 

  • Laurencet FM, Anchisi S, Tullen E, Dietrich PY. Mental neuropathy: report of five cases and review of the literature. Crit Rev Oncol Hematol. 2000;34(1):71–9.

    Article  PubMed  Google Scholar 

  • Lawson W, Reino AJ. Isolated sphenoid sinus disease: an analysis of 132 cases. Laryngoscope. 1997;107(12 Pt 1):1590–5.

    Article  PubMed  Google Scholar 

  • Lecky BR, Hughes RA, Murray NM. Trigeminal sensory neuropathy. A study of 22 cases. Brain. 1987;110(Pt 6):1463–85.

    Article  PubMed  Google Scholar 

  • Lorente Ramos RM, Azpeitia Armán J, Arévalo Galeano N, Muñoz Hernández A, García Gómez JM, Gredilla Molinero J. Dual energy X-ray absorptiometry: Fundamentals, methodology, and clinical applications. Radiologia 2012;54:410–23.

    Google Scholar 

  • Lundberg PO, Werner I. Trigeminal sensory neuropathy in systemic lupus erythematosus. Acta Neurol Scand. 1972;48(3):330–40.

    Article  PubMed  Google Scholar 

  • Lury KM, Smith JK, Matheus MG, Castillo M. Neurosarcoidosis – review of imaging findings. Semin Roentgenol. 2004;39(4):495–504.

    Article  PubMed  Google Scholar 

  • Macfarlane GJ, Kronisch C, Dean LE, Atzeni F, Häuser W, Fluß E, et al. EULAR revised recommendations for the management of fibromyalgia. Ann Rheum Dis. 2017;76(2):318–28.

    Article  PubMed  Google Scholar 

  • Magrinelli F, Zanette G, Tamburin S. Neuropathic pain: diagnosis and treatment. Pract Neurol. 2013;13(5):292–307. 2nd ed.

    Article  PubMed  Google Scholar 

  • Margolese HC, Chouinard G, Kolivakis TT, Beauclair L, Miller R. Tardive dyskinesia in the era of typical and atypical antipsychotics. Part 1: pathophysiology and mechanisms of induction. Can J Psychiatry. 2005;50(9):541–7.

    Article  PubMed  Google Scholar 

  • Marmura MJ, Silberstein SD. Headaches caused by nasal and paranasal sinus disease. Neurol Clin. 2014;32(2):507–23.

    Article  PubMed  Google Scholar 

  • Massey EW, Moore J, Schold SCJ. Mental neuropathy from systemic cancer. Neurology. 1981;31(10):1277–81.

    Article  PubMed  Google Scholar 

  • McCarthy GM, Skillings JR. Jaw and other orofacial pain in patients receiving vincristine for the treatment of cancer. Oral Surg Oral Med Oral Pathol. 1992;74(3):299–304.

    Article  PubMed  Google Scholar 

  • McCollister K, Hopper B, Michel M. Sinonasal neoplasms: update on classification, imaging features, and management. Appl Radiol. 2015;44:1–9.

    Google Scholar 

  • McKay-Davies I, Buchanan MA, Prinsley PR. An unusual headache: sphenoiditis in children and adolescents. Int J Pediatr Otorhinolaryngol. 2011;75(12):1486–91. Elsevier Ireland Ltd.

    Article  PubMed  Google Scholar 

  • McMillan R, Forssell H, Buchanan JA, Glenny AM, Weldon JC, Zakrzewska JM. Interventions for treating burning mouth syndrome. Cochrane Database Syst Rev. 2016;11:CD002779.

    PubMed  Google Scholar 

  • Mehdorn HM. Deep brain stimulation for dystonia: review of the literature. J Neurosurg Sci. 2016;60(2):199–210.

    PubMed  Google Scholar 

  • Mellgren SI, Conn DL, Stevens JC, Dyck PJ. Peripheral neuropathy in primary Sjögren’s syndrome. Neurology. 1989;39(3):390–4.

    Article  PubMed  Google Scholar 

  • Mendes PHC, Fonseca NG, Martelli DRB, Bonan PRF, de Almeida LKY, de Melo LA, et al. Orofacial manifestations in patients with sickle cell anemia. Quintessence Int. 2011;42(8):701–9.

    PubMed  Google Scholar 

  • Moazzam AA, Habibian M. Patients appearing to dental professionals with orofacial pain arising from intracranial tumors: a literature review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114(6):749–55.

    Article  PubMed  Google Scholar 

  • Mori K. The wide spectrum of clinical manifestations in Sjogren’s syndrome-associated neuropathy. Brain. 2005;128(11):2518–34.

    Article  PubMed  Google Scholar 

  • Morley S, Williams A, Eccleston C. Examining the evidence about psychological treatments for chronic pain: time for a paradigm shift? Pain. 2013;154(10):1929–31. International Association for the Study of Pain.

    Article  PubMed  Google Scholar 

  • Mudgil SP, Wise SW, Hopper KD, Kasales CJ, Mauger D, Fornadley JA. Correlation between presumed sinusitis-induced pain and paranasal sinus computed tomographic findings. Ann Allergy Asthma Immunol. 2002;88(2):223–6.

    Article  PubMed  Google Scholar 

  • Mulry JT, Cerbin J, Spencer DL. Alcoholic facial neuralgia: report of three cases. J Am Dent Assoc. 1986;112(6):847–8. Elsevier Masson SAS.

    Article  PubMed  Google Scholar 

  • Musheer Hussain S, editor. Logan Turner’s diseases of the nose, throat and ear: head and neck surgery. 11th ed. London: CRC Press; 2015.

    Google Scholar 

  • Nakayama T, Otori N, Komori M, Takayanagi H, Moriyama H. Primary localized amyloidosis of the nose. Auris Nasus Larynx. 2012;39(1):107–9.

    Article  PubMed  Google Scholar 

  • Napenas JJ, Rouleau TS. Oral complications of Sjogren’s syndrome. Oral Maxillofac Surg Clin North Am. 2014;26(1):55–62.

    Article  PubMed  Google Scholar 

  • Nasri-Heir C, Khan J, Heir GM. Topical medications as treatment of neuropathic orofacial pain. Dent Clin North Am. 2013;57(3):541–53.

    Article  PubMed  Google Scholar 

  • Nimnuan C, Rabe-Hesketh S, Wessely S, Hotopf M. How many functional somatic syndromes? J Psychosom Res. 2001;51(4):549–57.

    Article  PubMed  Google Scholar 

  • O’Neill F, Nurmikko T, Sommer C. Other facial neuralgias. Cephalalgia. 2017;37(7):658–69.

    Article  PubMed  Google Scholar 

  • Olney RK. Neuropathies associated with connective tissue disease. Semin Neurol. 1998;18(1):63–72.

    Article  PubMed  Google Scholar 

  • Owosho AA, Xu B, Kadempour A, Yom SK, Randazzo J, Ghossein RA, et al. Metastatic solid tumors to the jaw and oral soft tissue: a retrospective clinical analysis of 44 patients from a single institution. J Craniomaxillofac Surg. 2016;44:1047.

    Article  PubMed  PubMed Central  Google Scholar 

  • Panagopoulos N, Leivaditis V, Koletsis E, Prokakis C, Alexopoulos P, Baltayiannis N, et al. Pancoast tumors: characteristics and preoperative assessment. J Thorac Dis. 2014;6(Suppl 1):S108–15.

    PubMed  PubMed Central  Google Scholar 

  • Paraskevas KI, Boumpas DT, Vrentzos GE, Mikhailidis DP. Oral and ocular/orbital manifestations of temporal arteritis: a disease with deceptive clinical symptoms and devastating consequences. Clin Rheumatol. 2006;26(7):1044–8.

    Article  PubMed  Google Scholar 

  • Patel S, Choyee S, Uyanne J, Nguyen AL, Lee P, Sedghizadeh PP, et al. Non-exposed bisphosphonate-related osteonecrosis of the jaw: a critical assessment of current definition, staging, and treatment guidelines. Oral Dis. 2012;18(7):625–32.

    Article  PubMed  Google Scholar 

  • Pembroke CA, Byrne A, Lester JF, Button M. Persistent unilateral facial pain in lung cancer patients with mediastinal nodal involvement. Lung Cancer. 2013;82(1):173–5.

    Article  PubMed  Google Scholar 

  • Phillips K, Clauw DJ. Central pain mechanisms in chronic pain states – maybe it is all in their head. Best Pract Res Clin Rheumatol. 2011;25(2):141–54.

    Article  PubMed  PubMed Central  Google Scholar 

  • Pimentel MJ, Gui MS, Martins de Aquino LM, Rizzatti-Barbosa CM. Features of temporomandibular disorders in fibromyalgia syndrome. Cranio. 2013;31(1):40–5.

    Article  PubMed  Google Scholar 

  • Pisani A, Bernardi G, Ding J, Surmeier DJ. Re-emergence of striatal cholinergic interneurons in movement disorders. Trends Neurosci. 2007;30(10):545–53.

    Article  PubMed  Google Scholar 

  • Plaza-Villegas F, Heir G, Markman S, Khan J, Noma N, Benoliel R, et al. Topical pregabalin and diclofenac for the treatment of neuropathic orofacial pain in rats. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114(4):449–56.

    Article  PubMed  Google Scholar 

  • Quartarone A, Hallett M. Emerging concepts in the physiological basis of dystonia. Mov Disord. 2013;28(7):958–67.

    Article  PubMed  PubMed Central  Google Scholar 

  • Queiroz LP. Worldwide epidemiology of fibromyalgia. Curr Pain Headache Rep. 2013;17(8):356.

    Article  PubMed  Google Scholar 

  • Ravindran M, Baraniuk JN. The sinus headache explained. Curr Allergy Asthma Rep. 2010;10(3):202–9. 3rd ed.

    Article  PubMed  Google Scholar 

  • Reeves AG, Swenson RS. Disorders of the nervous system [Internet]. 2008. Available from https://www.dartmouth.edu/~dons/index.html.

  • Reutens DC. Burning oral and mid-facial pain in ventral pontine infarction. Aust N Z J Med. 1990;20(3):249–50.

    Article  PubMed  Google Scholar 

  • Rief W, Isaac M. The future of somatoform disorders: somatic symptom disorder, bodily distress disorder or functional syndromes? Curr Opin Psychiatry. 2014;27(5):315–9.

    Article  PubMed  Google Scholar 

  • Robinson LJ, Durham J, Newton JL. A systematic review of the comorbidity between Temporomandibular Disorders and Chronic Fatigue Syndrome. J Oral Rehabil. 2015;43(4):306–16.

    Article  PubMed  Google Scholar 

  • Romero-Reyes M, Teruel A, Ye Y. Cancer and referred facial pain. Curr Pain Headache Rep. 2015;19(8):491.

    Article  Google Scholar 

  • Ruggiero SL, Dodson TB, Fantasia J, Goodday R, Aghaloo T, Mehrotra B, et al. American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw – 2014 update. J Oral Maxillofac Surg. 2014;72:1938–56.

    Article  PubMed  Google Scholar 

  • Ruoppi P, Seppä J, Pukkila M, Nuutinen J. Isolated sphenoid sinus diseases: report of 39 cases. Arch Otolaryngol Head Neck Surg. 2000;126(6):777–81.

    Article  PubMed  Google Scholar 

  • Saeed AB, Shuaib A, Al-Sulaiti G, Emery D. Vertebral artery dissection: warning symptoms, clinical features and prognosis in 26 patients. Can J Neurol Sci. 2000;27(4):292–6.

    Article  PubMed  Google Scholar 

  • Scala A, Checchi L, Montevecchi M, Marini I, Giamberardino MA. Update on burning mouth syndrome: overview and patient management. Crit Rev Oral Biol Med. 2003;14(4):275–91.

    Article  PubMed  Google Scholar 

  • Schreiber CP, Hutchinson S, Webster CJ, Ames M, Richardson MS, Powers C. Prevalence of migraine in patients with a history of self-reported or physician-diagnosed “sinus” headache. Arch Intern Med. 2004;164(16):1769–72.

    Article  PubMed  Google Scholar 

  • Scully C, Flint S, Bagan J, Porter S, Moos K. Haematological disease. In: Oral and maxillofacial diseases. London: CRC Press; 2013. p. 24–37.

    Google Scholar 

  • Shakir HJ, Davies JM, Shallwani H, Siddiqui AH, Levy EI. Carotid and vertebral dissection imaging. Curr Pain Headache Rep. 2016;20:1–9.

    Google Scholar 

  • Shapshay SM, Elber E, Strong MS. Occult tumors of the infratemporal fossa: report of seven cases appearing as preauricular facial pain. Arch Otolaryngol. 1976;102(9):535–8.

    Article  PubMed  Google Scholar 

  • Sharma OP. Cardiac and neurologic dysfunction in sarcoidosis. Clin Chest Med. 1997;18(4):813–25.

    Article  PubMed  Google Scholar 

  • Sheikh HU. Headache in intracranial and cervical artery dissections. Curr Pain Headache Rep. 2016;20(2):20.

    Article  Google Scholar 

  • Silberstein SD, Lipton RB, Dodick D, Wolff HG. Wolff’s headache and other head pain. 8th ed. Oxford/New York: Oxford University Press; 2008.

    Google Scholar 

  • Silbert PL, Mokri B, Schievink WI. Headache and neck pain in spontaneous internal carotid and vertebral artery dissections. Neurology. 1995;45(8):1517–22.

    Article  PubMed  Google Scholar 

  • Slade GD, Fillingim RB, Sanders AE, Bair E, Greenspan JD, Ohrbach R, et al. Summary of findings from the OPPERA prospective cohort study of incidence of first-onset temporomandibular disorder: implications and future directions. J Pain. 2013;14(12 Suppl):T116–24.

    Article  PubMed  Google Scholar 

  • Smith L, Osborne RF. Facial sarcoidosis presenting as atypical facial pain. Ear Nose Throat J. 2006;85(9):574–8.

    PubMed  Google Scholar 

  • Smith RM, Hassan A, Robertson CE. Numb chin syndrome. Curr Pain Headache Rep. 2015;19(9):44.

    Article  PubMed  Google Scholar 

  • Solaro C, Brichetto G, Battaglia MA, Messmer Uccelli M, Mancardi GL. Antiepileptic medications in multiple sclerosis: adverse effects in a three-year follow-up study. Neurol Sci. 2005;25(6):307–10.

    Article  PubMed  Google Scholar 

  • Steere AC, Strle F, Wormser GP, Hu LT, Branda JA, Hovius JWR, et al. Lyme borreliosis. Nat Rev Dis Primers. 2016;2:1–19. Nature Publishing Group. Macmillan Publishers Limited.

    Google Scholar 

  • Stone KL, Seeley DG, Lui L-Y, Cauley JA, Ensrud K, Browner WS, et al. BMD at multiple sites and risk of fracture of multiple types: long-term results from the Study of Osteoporotic Fractures. J Bone Miner Res. 2003;18(11):1947–54.

    Article  PubMed  Google Scholar 

  • Strub GM, Moore JE, Huang AT, Stevenson AW, Reiter ER. Chronic facial pain and Meckel cave masses as the initial presentation of neurosarcoidosis: a case report. Ear Nose Throat J. 2013;92(12):558–65.

    PubMed  Google Scholar 

  • Stys PK. Multiple sclerosis: autoimmune disease or autoimmune reaction? Can J Neurol Sci. 2010;37(Suppl 2):S16–23.

    Article  PubMed  Google Scholar 

  • Sweeney CJ, Gilden DH. Ramsay Hunt syndrome. J Neurol Neurosurg Psychiatry. 2001;71(2):149–54.

    Article  PubMed  PubMed Central  Google Scholar 

  • Taiminen T, Kuusalo L, Lehtinen L, Forssell H, Hagelberg N, Tenovuo O, et al. Psychiatric (axis I) and personality (axis II) disorders in patients with burning mouth syndrome or atypical facial pain. Scand J Pain. 2011;2(4):155–60.

    Article  PubMed  Google Scholar 

  • Tan EK, Jankovic J. Botulinum toxin A in patients with oromandibular dystonia: long-term follow-up. Neurology. 1999;53(9):2102–7.

    Article  PubMed  Google Scholar 

  • Tanabe LM, Kim CE, Alagem N, Dauer WT. Primary dystonia: molecules and mechanisms. Nat Rev Neurol. 2009;5(11):598–609.

    Article  PubMed  PubMed Central  Google Scholar 

  • Tanner CM, Goldman SM. Epidemiology of movement disorders. Curr Opin Neurol. 1994;7(4):340–5.

    Article  PubMed  Google Scholar 

  • Tarabichi M. Characteristics of sinus-related pain. Otolaryngol Head Neck Surg. 2000;122(6):842–7.

    Article  PubMed  Google Scholar 

  • Teasdall RD, Frayha RA, Shulman LE. Cranial nerve involvement in systemic sclerosis (scleroderma): a report of 10 cases. Medicine. 1980;59(2):149–59.

    Article  PubMed  Google Scholar 

  • Thenganatt MA, Fahn S. Botulinum toxin for the treatment of movement disorders. Curr Neurol Neurosci Rep. 2012;12(4):399–409.

    Article  PubMed  Google Scholar 

  • Toda K. The term of functional somatic syndrome should be changed to the term of central sensitivity syndrome. Pain Pract. 2012;12(1):83.

    Article  PubMed  Google Scholar 

  • Toffoli D, Elysée S, Dominguez MJ, Lanthier S. Cardioembolism: a rare cause of jaw claudication. Can J Neurol Sci. 2007;34(2):254–5.

    Article  PubMed  Google Scholar 

  • Tracy JA, Dyck PJB. The spectrum of diabetic neuropathies. Phys Med Rehabil Clin N Am. 2008;19(1):1–26.

    Article  PubMed  PubMed Central  Google Scholar 

  • Traynor AE, Gertz MA, Kyle RA. Cranial neuropathy associated with primary amyloidosis. Ann Neurol. 1991;29(4):451–4.

    Article  PubMed  Google Scholar 

  • Trumpy IG, Lyberg T. Temporomandibular joint dysfunction and facial pain caused by neoplasms. Report of three cases. Oral Surg Oral Med Oral Pathol. 1993;76(2):149–52.

    Article  PubMed  Google Scholar 

  • Truong D. Botulinum toxins in the treatment of primary focal dystonias. J Neurol Sci. 2012;316(1–2):9–14. Elsevier B.V.

    Article  PubMed  Google Scholar 

  • Vestergaard P, Rejnmark L, Mosekilde L. Fracture risk associated with use of antiepileptic drugs. Epilepsia. 2004;45(11):1330–7.

    Article  PubMed  Google Scholar 

  • Waldman CW, Waldman SD, Waldman RA. Giant cell arteritis. Med Clin North Am. 2013;97(2):329–35.

    Article  PubMed  Google Scholar 

  • Walker PM. Ischemia/reperfusion injury in skeletal muscle. Ann Vasc Surg. 1991;5(4):399–402.

    Article  PubMed  Google Scholar 

  • Warren JW, Langenberg P, Clauw DJ. The number of existing functional somatic syndromes (FSSs) is an important risk factor for new, different FSSs. J Psychosom Res. 2013;74(1):12–7.

    Article  PubMed  Google Scholar 

  • Wasner G. Central pain syndromes. Curr Pain Headache Rep. 2010;14(6):489–96.

    Article  PubMed  Google Scholar 

  • Wasner G, Deuschl G. Pains in Parkinson disease – many syndromes under one umbrella. Nat Rev Neurol. 2012;8(5):284–94. Nature Publishing Group.

    Article  PubMed  Google Scholar 

  • Weiner HL. Multiple sclerosis is an inflammatory T-cell-mediated autoimmune disease. Arch Neurol. 2004;61(10):1613–5.

    Article  PubMed  Google Scholar 

  • Wessely S, White PD. There is only one functional somatic syndrome. Br J Psychiatry. 2004;185(2):95–6.

    Article  PubMed  Google Scholar 

  • Wessely S, Nimnuan C, Sharpe M. Functional somatic syndromes: one or many? Lancet. 1999;354(9182):936–9.

    Article  PubMed  Google Scholar 

  • West B, Jones NS. Endoscopy-negative, computed tomography-negative facial pain in a nasal clinic. Laryngoscope. 2001;111(4 Pt 1):581–6.

    Article  PubMed  Google Scholar 

  • Weyand CM, Goronzy JJ. Giant-cell arteritis and polymyalgia rheumatica. N Engl J Med. 2014;371(1):50–7.

    Article  PubMed  PubMed Central  Google Scholar 

  • Williams AC de C, Craig KD. Updating the definition of pain. Pain. 2016;157(11):2420–3.

    Article  PubMed  Google Scholar 

  • Wolańska-Klimkiewicz E, Szymańska J, Bachanek T. Orofacial symptoms related to boreliosis – case report. Ann Agric Environ Med. 2010;17(2):319–21.

    PubMed  Google Scholar 

  • Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, et al. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum. 1990;33(2):160–72.

    Article  PubMed  Google Scholar 

  • Wolfe F, Clauw DJ, Fitzcharles M-A, Goldenberg DL, Katz RS, Mease P, et al. The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity. Arthritis Care Res. 2010;62(5):600–10.

    Article  Google Scholar 

  • Wolfe F, Clauw DJ, Fitzcharles M-A, Goldenberg DL, Häuser W, Katz RS, et al. Fibromyalgia criteria and severity scales for clinical and epidemiological studies: a modification of the ACR Preliminary Diagnostic Criteria for Fibromyalgia. J Rheumatol. 2011;38(6):1113–22.

    Article  PubMed  Google Scholar 

  • Wolfe F, Clauw DJ, Fitzcharles M-A, Goldenberg DL, Häuser W, Katz RL, et al. Revisions to the 2010/2011 fibromyalgia diagnostic criteria. Semin Arthritis Rheum. 2016;46(3):319–29. Elsevier.

    Article  PubMed  Google Scholar 

  • Woolf CJ. Central sensitization: implications for the diagnosis and treatment of pain. Pain. 2011;152(S):S2–S15. International Association for the Study of Pain.

    Article  PubMed  Google Scholar 

  • World Health Organisation. Chronic rheumatic conditions [Internet]. [cited 13 Dec 2017]. Available from http://www.who.int/chp/topics/rheumatic/en/.

  • Yagihashi S, Mizukami H, Sugimoto K. Mechanism of diabetic neuropathy: where are we now and where to go? J Diabetes Investig. 2011;2(1):18–32.

    Article  PubMed  Google Scholar 

  • Yawn BP, Wollan PC, St Sauver JL, Butterfield LC. Herpes zoster eye complications: rates and trends. Mayo Clin Proc. 2013;88(6):562–70.

    Article  PubMed  Google Scholar 

  • Yunus MB. Fibromyalgia and overlapping disorders: the unifying concept of central sensitivity syndromes. Semin Arthritis Rheum. 2007;36(6):339–56.

    Article  PubMed  Google Scholar 

  • Yunus MB. Central sensitivity syndromes: a new paradigm and group nosology for fibromyalgia and overlapping conditions, and the related issue of disease versus illness. Semin Arthritis Rheum. 2008;37(6):339–52.

    Article  PubMed  Google Scholar 

  • Yunus MB. Editorial review: an update on central sensitivity syndromes and the issues of nosology and psychobiology. Curr Rheumatol Rev. 2015;11(2):70–85.

    Article  PubMed  Google Scholar 

  • Zadik Y, Vainstein V, Heling I, Neuman T, Drucker S, Elad S. Cytotoxic chemotherapy-induced odontalgia: a differential diagnosis for dental pain. J Endod. 2010;36(9):1588–92.

    Article  PubMed  Google Scholar 

  • Zhang X, Hamadeh IS, Song S, Katz J, Moreb JS, Langaee TY, et al. Osteonecrosis of the jaw in the United States Food and Drug Administration’s Adverse Event Reporting System (FAERS). J Bone Miner Res. 2016;31(2):336–40.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Oral Medicine Unit, Eastman Dental Hospital, University College London Hospitals NHS Trust, London, UK

    Martina K. Shephard

  2. Center for Temporomandibular Disorders and Orofacial Pain, Rutgers School of Dental Medicine, Newark, NJ, USA

    Gary Heir

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Correspondence to Martina K. Shephard .

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Editors and Affiliations

  1. UWA Dental School and Oral Health Centre of Western Australia, Faculty of Health and Medical Sciences University of Western Australia, Perth, WA, Australia

    Camile S. Farah

  2. UWA Dental School and Oral Health Centre of Western Australia, Faculty of Health and Medical Sciences University of Western Australia, Perth, WA, Australia

    Ramesh Balasubramaniam

  3. Oral Anatomy, Medicine, and Surgery Section Melbourne Dental School, Faculty of Medicine, Dentistry and Health Sciences The University of Melbourne, Carlton, VIC, Australia

    Michael J. McCullough

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  1. UWA Dental School and Oral Health Centre of Western Australia, University of Western Australia, Perth WA, Australia

    Ramesh Balasubramaniam

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Shephard, M.K., Heir, G. (2019). Orofacial Pain in the Medically Complex Patient. In: Farah, C., Balasubramaniam, R., McCullough, M. (eds) Contemporary Oral Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-72303-7_38

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