Synonyms
No terms are synonymous with primary pleural liposarcoma.
Definition
Liposarcoma (LPS) is one of the most common types of sarcomas seen in adults. It is believed that LPS are derived from the residual rests of primitive mesenchymal tissue; however, on rare occasions they may also develop from a pre-existing lipoma. They are commonly found as a primary tumor in the deep soft tissues of the proximal extremities, and retroperitoneum. Metastasis to the lung in not uncommon; however, primary LPS in the lung is rare, especially the pleura.
Clinical Features
Incidence
Primary pleural LPS is exceedingly rare with less than 20 cases reported
Age
Age of presentation ranges from 19 to 80 years of age, with a median age of 50 years.
Sex
Older men are predominately affected; however, it may occur in women as well.
Site
Pleura
Treatment
Treatment consists of surgical resection, radiation, or chemotherapy. Radiation therapy seems to show some benefit.
Outcome
Determination of prognosis has...
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References and Further Reading
Cagle, P. T., et al. (2004). Color atlas and text of pulmonary pathology (1st ed.). Philadelphia: Lippincott Williams & Wilkins.
Dagli, A. F., Pehlivan, S., & Ozercan, M. R. (2010). Pleural liposarcoma mimicking carcinoma in pleural effusion cytology: A case report. Acta Cytologica, 54, 601–604.
Elsayed, H., & Gosney, J. (2011). A massive pleural-based tumour: The challenge of diagnosis. Revista Portuguesa de Pneumologia, 17, 275–277.
Gattuso, P., et al. (2010). Differential diagnosis in surgical pathology (2nd ed.). Philadelphia: Saunders.
Okby, N. T., & Travis, W. D. (2000). Liposarcoma of the pleural cavity: Clinical and pathologic features of 4 cases with a review of the literature. Archives of Pathology and Laboratory Medicine, 124, 699–703.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this entry
Cite this entry
Marquez, C.P., Allen, T.C. (2018). Liposarcoma, Primary Pleural. In: Allen, T.C., Suster, S. (eds) Pathology of the Pleura and Mediastinum. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-66796-6_2883
Download citation
DOI: https://doi.org/10.1007/978-3-319-66796-6_2883
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-66795-9
Online ISBN: 978-3-319-66796-6
eBook Packages: MedicineReference Module Medicine