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MEG/EEG Data Analysis Using EEGLAB

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Abstract

EEGLAB (sccn.ucsc.edu/eeglab) is an easily extensible, highly evolved, and widely used open-source environment for signal processing and visualization of electroencephalographic data running on MATLAB (The MathWorks, Inc.). Methods central to EEGLAB include time and time-frequency analysis and visualization of individual datasets and complete studies, independent component analysis (ICA), and rich tools for connectivity analysis, brain-computer interface (BCI) development, and fusion and joint analysis of simultaneously recorded motion capture and brain data. We introduce a new MEEG plug-in that enables MEG and simultaneously recorded MEG/EEG (MEEG) data to be readily analyzed using EEGLAB. Its use is demonstrated by the analysis of an MEEG dataset. Here we show a first ICA decomposition of an MEEG dataset and use MEEG plotting tools to localize and evaluate maximally independent joint MEG/EEG component processes in the data. The analysis naturally recovers a range of artifact sources, as well as brain sources common to MEG and EEG, as well as sources primarily visible only to EEG.

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References

  • Ahlfors SP, Han J, Belliveau JW, Hämäläinen MS (2010) Sensitivity of MEG and EEG to source orientation. Brain Topogr 23:227–232

    Article  Google Scholar 

  • Akalin Acar Z, Gençer NG (2004) An advanced boundary element method (BEM) implementation for the forward problem of electromagnetic source imaging. Phys Med Biol 49:5011–5028

    Article  Google Scholar 

  • Akalin Acar Z, Makeig SD (2010) Neuroelectromagnetic forward head modeling toolbox. J Neurosci Methods 190:258–270

    Article  Google Scholar 

  • Bigdely-Shamlo N, Kreutz-Delgado K, Kothe C, Makeig SD (2013a) Towards an EEG search engine. In: IEEE global conference on signal and information processing (GlobalSIP), Austin, pp 25–28

    Google Scholar 

  • Bigdely-Shamlo N, Kreutz-Delgado K, Robbins K, Miyakoshi M, Westerfield M, Bel-Bahar T, Kothe CA, His J, Makeig SD (2013b) Hierarchical event descriptor (HED) tags for analysis of event-related EEG studies. In: IEEE global conference on signal and information processing (GlobalSIP), Austin, pp 1–4

    Google Scholar 

  • Bigdely-Shamlo N, Mullen T, Kreutz-Delgado K, Makeig SD (2013c) Measure projection analysis: a probabilistic approach to EEG source comparison and multi-subject inference. NeuroImage 72:287–303

    Article  Google Scholar 

  • Bledowski C, Kaiser J, Wibral M, Yildiz-Erzberger K, Rahm B (2012) Separable neural bases for subprocesses of recognition in working memory. Cereb Cortex 22:1950–1958

    Article  Google Scholar 

  • Dale AM, Sereno MI (1993) Improved localization of cortical activity by combining EEG and MEG with MRI cortical surface reconstruction: a linear approach. J Cogn Neurosci 5:162–176

    Article  Google Scholar 

  • Delorme A, Makeig SD (2004) EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. J Neurosci Methods 134:9–21

    Article  Google Scholar 

  • Delorme A, Mullen T, Kothe CA, Acar ZA, Bigdely-Shamlo N, Vankov A, Makeig SD (2011) EEGLAB, SIFT, NFT, BCILAB, and ERICA: new tools for advanced EEG processing. Comput Intell Neurosci 2011:1–12

    Article  Google Scholar 

  • Delorme A, Palmer J, Onton J, Oostenveld R, Makeig SD (2012) Independent EEG sources are dipolar. PLoS One 7:e30135

    Article  Google Scholar 

  • Fife AA (1999) Synthetic gradiometer systems for MEG. IEEE Trans Appl Supercond 9:4063–4068

    Article  Google Scholar 

  • Fischl B, Sereno MI, Dale AM (1999) Cortical surface-based analysis. II: inflation, flattening, and a surface-based coordinate system. NeuroImage 9:195–207

    Article  Google Scholar 

  • Fuchs M, Wagner M, Wischmann HA, Köhler T, Theissen A, Drenckhahn R, Buchner H (1998) Improving source reconstructions by combining bioelectric and biomagnetic data. Electroencephalogr Clin Neurophysiol 107:93–111

    Article  Google Scholar 

  • Hämäläinen MS, Sarvas J (1989) Realistic conductivity geometry model of the human head for interpretation of neuromagnetic data. IEEE Trans Biomed Eng 36:165–171

    Article  Google Scholar 

  • Hanke M, Halchenko YO (2011) Neuroscience runs on GNU/Linux. Front Neuroinform 5:8

    Article  Google Scholar 

  • Huang M-X, Song T, Hagler DJ Jr, Podgorny I, Jousmaki V, Cui L, Gaa K, Harrington DL, Dale AM, Lee RR, Elman J, Halgren E (2007) A novel integrated MEG and EEG analysis method for dipolar sources. NeuroImage 37:731–748

    Article  Google Scholar 

  • Ikeda S, Toyama K (2000) Independent component analysis for noisy data–MEG data analysis. Neural Netw 13:1063–1074

    Article  Google Scholar 

  • Kothe CA, Makeig SD (2010) BCILAB: a BCI/EEG research framework. In: Proceedings of the fourth international brain-computer interface meeting

    Google Scholar 

  • Liu AK, Belliveau JW, Dale AM (1998) Spatiotemporal imaging of human brain activity using functional MRI constrained magnetoencephalography data: Monte Carlo simulations. Proc Natl Acad Sci U S A 95:8945–8950

    Article  Google Scholar 

  • Makeig SD, Bell AJ, Jung T-P (1996) Independent component analysis of electroencephalographic data. Adv Neural Info Proc Syst 8:145–151

    Google Scholar 

  • Makeig SD, Debener S, Onton J, Delorme A (2004) Mining event-related brain dynamics. Trends Cogn Sci 8:204–210

    Article  Google Scholar 

  • McKeown MJ, Makeig SD, Brown GG, Jung T-P, Kindermann SS, Bell AJ, Sejnowski TJ (1998) Analysis of fMRI data by blind separation into independent spatial components. Hum Brain Mapp 6:160–188

    Article  Google Scholar 

  • Menninghaus E, Lütkenhöner B (1995) How silent are deep and radial sources in neuromagnetic measurements. In: Baumgartner C (ed) Biomagnetism: fundamental research and clinical applications. Elsevier Science, Vienna, pp 352–356

    Google Scholar 

  • Palmer JA (2006) Variational and scale mixture representations of non-Gaussian densities for estimation in the Bayesian linear model: sparse coding, independent component analysis, and minimum entropy segmentation. University of California, San Diego

    Google Scholar 

  • Palmer JA, Kreutz-Delgado K, Rao BD, Makeig SD (2007) Modeling and estimation of dependent subspaces with non-radially symmetric and skewed densities. In: Independent component analysis and signal separation. Springer, Heidelberg, pp 97–104

    Chapter  Google Scholar 

  • Pernet CR, Chauveau N, Gaspar C, Rousselet GA (2011) LIMO EEG: a toolbox for hierarchical LInear MOdeling of ElectroEncephaloGraphic data. Comput Intell Neurosci 2011:1–11

    Article  Google Scholar 

  • Takada K, Nomura K, Ono Y, Kurosawa M, Ishiyama A, Kasai N, Nakasato N (2000) MEG/EEG hybrid method for source localization of a dipole with radial component. Papers of technical meeting on magnetics MAG-00:23–28

    Google Scholar 

  • Trujillo-Barreto NJ, Aubert-Vázquez E, Penny WD (2008) Bayesian M/EEG source reconstruction with spatio-temporal priors. NeuroImage 39:318–335

    Article  Google Scholar 

  • Tsai AC, Liou M, Jung T-P, Onton JA, Cheng PE, Huang C-C, Duann J-R, Makeig SD (2006) Mapping single-trial EEG records on the cortical surface through a spatiotemporal modality. NeuroImage 32:195–207

    Article  Google Scholar 

  • Tsai AC, Jung T-P, Chien VSC, Savostyanov AN, Makeig SD (2014) Cortical surface alignment in multi-subject spatiotemporal independent EEG source imaging. NeuroImage 87:297–310.

    Article  Google Scholar 

  • Tukey PA, Tukey JW (1981) Graphical display of data sets in three or more dimensions. In: Barnett V (ed) Interpreting Multivariate Data. Wiley, Chichester

    MATH  Google Scholar 

  • Whitmer D, Worrell G, Stead M, Lee IK, Makeig SD (2010) Utility of independent component analysis for interpretation of intracranial EEG. Front Hum Neurosci 4:184

    Article  Google Scholar 

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Acknowledgements

This work was funded by a gift from The Swartz Foundation (Old Field, NY) and by the National Institutes of Health, USA, Grant R01 NS047293-09, and National Science Foundation, USA, Grant BCS-1460885.

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Correspondence to John R. Iversen .

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Iversen, J.R., Makeig, S. (2019). MEG/EEG Data Analysis Using EEGLAB. In: Supek, S., Aine, C. (eds) Magnetoencephalography. Springer, Cham. https://doi.org/10.1007/978-3-319-62657-4_8-1

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  • DOI: https://doi.org/10.1007/978-3-319-62657-4_8-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-62657-4

  • Online ISBN: 978-3-319-62657-4

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