Generic Name
Desvenlafaxine
Brand Name
Pristiq, Khedzla
Class
Antidepressants, serotonin norepinephrine reuptake inhibitors.
Proposed Mechanism(s) of Action
Increases serotonin and norepinephrine by blocking both serotonin and norepinephrine reuptake pumps.
Indication
Major depressive disorder.
Off-Label Use
Neuropathic pain, chronic pain, generalized anxiety disorder, stress urinary incontinence, and fibromyalgia.
Side Effects
Serious
Seizures, hypomania, and suicidal ideation.
Common
Nausea, headache, diarrhea, dry mouth, constipation, fatigue.
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References and Readings
Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.
Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.
Additional Information
Drug Interaction Effects. http://www.drugs.com/drug_interactions.html
Drug Molecule Images. http://www.worldofmolecules.com/drugs/
Free Drug Online and PDA Software. www.medscapepsychiatry.com
Free Drug Online and PDA Software. www.epocrates.com
Gene-Based Estimate of Drug interactions. http://mhc.daytondcs.com:8080/cgi bin/ddiD4?ver=4&task=getDrugList
Pill Identification. http://www.drugs.com/pill_identification.html
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Gonzalez, E.A. (2018). Desvenlafaxine. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_9274
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DOI: https://doi.org/10.1007/978-3-319-57111-9_9274
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