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Guillain-Barré Syndrome

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Synonyms

Acute febrile polyneuritis; Acute infective polyneuritis; Acute inflammatory demyelinating polyradiculoneuropathy (AIDP); Idiopathic polyneuritis; Landry-Guillain-Barré syndrome; Landry-Guillain-Barré-Strohl syndrome

Short Description or Definition

Guillain-Barré syndrome (GBS) is a monophasic illness of immune etiology that presents as an evolving sensorimotor polyneuropathy of varying severity as a result of an inflammation of the peripheral nerves and nerve roots. GBS is a major cause of acute ascending neuromuscular paralysis and is often associated with autonomic dysfunction.

Categorization

GBS is recognized as a heterogeneous syndrome with several variant forms (see Table 1). The commonest type of GBS is AIDP. Axonal subtypes include acute motor axonal neuropathy and acute motor and sensory axonal neuropathy. Variants include Miller Fisher syndrome (cranial nerve involvement, ataxia) and acute pan-dysautonomia.

Guillain-Barré Syndrome, Table 1 Frequency of features and...

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References and Readings

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Correspondence to Khan Fary .

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Fary, K., Ng, L. (2018). Guillain-Barré Syndrome. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_554

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