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Magnetic Resonance Spectroscopy

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Synonyms

MRS; Proton magnetic resonance spectroscopy

Definition

Magnetic resonance spectroscopy is a noninvasive study used to characterize tissues of the body. Like magnetic resonance imaging, MRS is based on the principle of nuclear magnetic resonance. It allows evaluation of metabolic activity in vivo.

Current Knowledge

MRS uses signals from metabolites such as N-acetyl aspartate, choline, creatine (Cr), glutamate, glutamine, lipids, amino acids, and lactate in the tissue examined. MRI uses signals from hydrogen. MRS is most commonly used to evaluate disorders of the central nervous system, but its indications and uses have been increasing with increasing frequency. MRS is not specific, but should be used in combination with clinical information and MRI. It has been shown to be helpful in diagnosing certain diseases. The results of MRS are graphed. The spectrum of resonances (peaks) is displayed on the x-axis as parts per million (ppm), and the amplitudes are measured on the y-axis...

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References and Readings

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Correspondence to Cindy B. Ivanhoe .

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Ivanhoe, C.B., Sanchez, A.D., Zasler, N.D. (2018). Magnetic Resonance Spectroscopy. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_49

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